Literature DB >> 5413331

In vitro studies of the suppression of delayed hypersensitivity by the induction of partial tolerance.

Y Borel, J R David.   

Abstract

Suppression of delayed hypersensitivity in vivo is correlated in vitro with the absence of macrophage migration inhibition in the presence of the antigen used to induce partial tolerance. The suppression of delayed hypersensitivity is antigen-specific in vivo as well as in vitro. The lymphocytes, and not the macrophages, are the cells involved in the induction of tolerance in terms of delayed hypersensitivity which is characterized by an absence of migratory factor activity.

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Year:  1970        PMID: 5413331      PMCID: PMC2138816          DOI: 10.1084/jem.131.3.603

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  13 in total

1.  IMMUNOLOGICAL SPECIFICITY OF THE SECONDARY RESPONSE WITH DINITROPHENYLATED PROTEINS.

Authors:  Z OVARY; B BENACERRAF
Journal:  Proc Soc Exp Biol Med       Date:  1963-10

2.  In vitro cell migration as a model for delayed hypersensitivity.

Authors:  M GEORGE; J H VAUGHAN
Journal:  Proc Soc Exp Biol Med       Date:  1962-11

3.  Studies of hypersensitivity to low molecular weight substances. III. The 2,4-dinitrophenyl group as a determinant in the preciptin reaction.

Authors:  H N EISEN; M E CARSTEN; S BELMAN
Journal:  J Immunol       Date:  1954-11       Impact factor: 5.422

4.  Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction.

Authors:  J R David
Journal:  Proc Natl Acad Sci U S A       Date:  1966-07       Impact factor: 11.205

5.  Selective and specific inhibition of 24 hour skin reactions in the guinea-pig. I. Immune deviation: description of the phenomenon and the effect of splenectomy.

Authors:  G L Asherson; S H Stone
Journal:  Immunology       Date:  1965-09       Impact factor: 7.397

6.  Macrophages from tolerant rabbits as mediators of a specific immunological response in vitro.

Authors:  G Harris
Journal:  Immunology       Date:  1967-02       Impact factor: 7.397

7.  Dissociation of immune responses by the induction of partial unresponsiveness. Relationship of PCA and complement-fixing antibody formation to the suppression of delayed hypersensitivity.

Authors:  Y Borel; M Fauconnet; P Miescher
Journal:  J Immunol       Date:  1967-05       Impact factor: 5.422

8.  Selective suppression of delayed hypersensitivity by the induction of immunologic tolerance.

Authors:  Y Borel; M Fauconnet; P A Miescher
Journal:  J Exp Med       Date:  1966-04-01       Impact factor: 14.307

9.  Immunochemical studies on the specificity of cellular hypersensitivity. The in vitro inhibition of peritoneal exudate cell migration by cehmically defined antigens.

Authors:  J R David; S F Schlossman
Journal:  J Exp Med       Date:  1968-12-01       Impact factor: 14.307

10.  Properties of guinea pig 7S antibodies. III. Identification of antibodies involved in complement fixation and hemolysis.

Authors:  K J BLOCH; F M KOURILSKY; Z OVARY; B BENACERRAF
Journal:  J Exp Med       Date:  1963-06-01       Impact factor: 14.307

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  11 in total

1.  The relation between the cell-mediated immunological response and the induction of circulating antibodies to collagen in guinea-pigs.

Authors:  G J Gentner; B C Adelmann
Journal:  Immunology       Date:  1976-07       Impact factor: 7.397

Review 2.  The biological activities of soluble lymphocyte products.

Authors:  E Pick; J L Turk
Journal:  Clin Exp Immunol       Date:  1972-01       Impact factor: 4.330

3.  Increased DNA synthesis in vitro in guinea-pigs unresponsive to DNP--skin protein conjugate.

Authors:  L Polak; A Polak; J R Frey
Journal:  Immunology       Date:  1974-07       Impact factor: 7.397

4.  The mechanism of tolerance in contact hypersensitivity to dinitrochlorobenzene in guinea-pigs.

Authors:  W J Halliday; B A Walters
Journal:  Clin Exp Immunol       Date:  1974-02       Impact factor: 4.330

5.  Migration inhibitory factor and the cellular basis of delayed-type hypersensitivity reactions.

Authors:  B R Bloom; L Jimenez
Journal:  Am J Pathol       Date:  1970-09       Impact factor: 4.307

6.  Cutaneous basophil (Jones-Mote) hypersensitivity after "tolerogenic" doses of intravenous ovalbumin in the guinea pig.

Authors:  H B Richerson
Journal:  J Exp Med       Date:  1971-09-01       Impact factor: 14.307

7.  The compartmentalization of antigen-reactive lymphocytes in desensitized guinea pigs.

Authors:  S F Schlossman; H A Levin; R E Rocklin; J R David
Journal:  J Exp Med       Date:  1971-09-01       Impact factor: 14.307

8.  Cell-mediated immunity and antibody responses in the respiratory tract after local and systemic immunization.

Authors:  R H Waldman; C S Henney
Journal:  J Exp Med       Date:  1971-08-01       Impact factor: 14.307

9.  Heterogeneity of the cellular immune response. I. Kinetics of lymphocyte stimulation during sensitization and recovery from tolerance.

Authors:  R C Bast; E J Manseau; H F Dvorak
Journal:  J Exp Med       Date:  1971-02-01       Impact factor: 14.307

10.  Immune response to chemically modified flagellin. 3. Enhanced cell-mediated immunity during high and low zone antibody tolerance to flagellin.

Authors:  C R Parish; F Y Liew
Journal:  J Exp Med       Date:  1972-02-01       Impact factor: 14.307

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