Literature DB >> 5409712

"Antidotal thirst": a response to intoxication.

D F Smith, S Balagura, M Lubran.   

Abstract

Albino rats increased their intake of water soon after they were given a load of 0.12 molar lithium chloride in the stomach. Alterations in blood volume and tonicity could not account for the magnitude of the thirst observed, which served to facilitate the renal excretion of the toxic lithium ions.

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Year:  1970        PMID： 5409712     DOI： 10.1126/science.167.3916.297

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  4 in total

1.  Voluntary lithium intake, antidotal thirst' and concurrent behavior of rats.

Authors:  R J Langham; G J Syme; L A Syme
Journal:  Br J Pharmacol       Date:  1975-11       Impact factor: 8.739

2.  Inhibition by lithium of the hydroosmotic action of vasopressin in the isolated perfused cortical collecting tubule of the rabbit.

Authors:  E Cogan; M Abramow
Journal:  J Clin Invest       Date:  1986-05       Impact factor: 14.808

3.  On the mechanism of lithium-induced diabetes insipidus in man and the rat.

Authors:  J N Forrest; A D Cohen; J Torretti; J M Himmelhoch; F H Epstein
Journal:  J Clin Invest       Date:  1974-04       Impact factor: 14.808

4.  Time course of lithium-induced alterations in renal and endocrine function in normal and Brattleboro rats with hypothalamic diabetes insipidus.

Authors:  R J Balment; I C Jones; I W Henderson
Journal:  Br J Pharmacol       Date:  1977-04       Impact factor: 8.739
  4 in total

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