Literature DB >> 5409642

L-asparaginase-deficient mutants of yeast.

G E Jones, R K Mortimer.   

Abstract

Yeast L-asparaginase is a multimeric enzyme for which only a single structural gene has been found. Fourteen mutants deficient in L-asparaginase have been isolated, and they have been located at one site on the genetic map of Saccharomyces cerevisiae. The L-asparaginase gene (aspl) is located about 18 centimorgans from a gene governing tryptophan synthesis (trp4) on fragment 2 of the map.

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Year:  1970        PMID： 5409642     DOI： 10.1126/science.167.3915.181

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

Review 1.  Genetic map of Saccharomyces cerevisiae, edition 9.

Authors:  R K Mortimer; D Schild
Journal:  Microbiol Rev       Date:  1985-09

Review 2.  Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine.

Authors:  Ji Zhang; Natalya N Pavlova; Craig B Thompson
Journal:  EMBO J       Date:  2017-04-18       Impact factor: 11.598

3.  A fine-structure map of the yeast l-asparaginase gene.

Authors:  G E Jones
Journal:  Mol Gen Genet       Date:  1973

4.  Biochemical properties of yeast L-asparaginase.

Authors:  G E Jones; R K Mortimer
Journal:  Biochem Genet       Date:  1973-06       Impact factor: 1.890

5.  Genetic map of Saccharomyces cerevisiae.

Authors:  R K Mortimer; D Schild
Journal:  Microbiol Rev       Date:  1980-12

6.  L-Asparaginase of Saccharomyces cerevisiae: an extracellular Enzyme.

Authors:  P C Dunlop; R J Roon
Journal:  J Bacteriol       Date:  1975-06       Impact factor: 3.490

7.  Genetic and physiological relationships between L-asparaginase I and asparaginase II in Saccharomyces cerevisiae.

Authors:  G E Jones
Journal:  J Bacteriol       Date:  1977-04       Impact factor: 3.490

8.  Genetics of expression of asparaginase II activity in Saccharomyces cerevisiae.

Authors:  G E Jones
Journal:  J Bacteriol       Date:  1977-02       Impact factor: 3.490

9.  L-Asparagine auxotrophs of Saccharomyces cerevisiae: genetic and phenotypic characterization.

Authors:  G E Jones
Journal:  J Bacteriol       Date:  1978-04       Impact factor: 3.490

10.  Asparaginase II of Saccharomyces cerevisiae: positive selection of two mutations that prevent enzyme synthesis.

Authors:  K W Kim; R J Roon
Journal:  J Bacteriol       Date:  1984-03       Impact factor: 3.490
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