Literature DB >> 54037

Relationship of the biosynthesis of alpha-fetoprotein, albumin, hemopexin, and haptoglobin to the growth state of fetal rat hepatocyte cultures.

S Sell, H Skelly, H L Leffert, U Muller-Eberhard, S Kida.   

Abstract

AFP and albumin are produced by arginine-synthesizing fetal rat hepatocytes in vitro. AFP and hemopexin production are coupled to hepatocellular proliferation, whereas albumin and haptoglobin production are not. During the cell cycle, AFP is synthesized prior to S and released prior to M. AFP may play a role in regulation of hepatocellular growth through estradiol binding and modulation of the intracellular concentration of lipoprotein (VLDL).

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Year:  1975        PMID： 54037     DOI： 10.1111/j.1749-6632.1975.tb25401.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  17 in total

1.  Regulation of rat liver maturation in vitro by glucocorticoids.

Authors:  J Y Chou; Y J Wan; T Sakiyama
Journal:  Mol Cell Biol       Date:  1988-01       Impact factor: 4.272

2.  Attachment and multiplication, morphology and protein production of human fetal primary liver cells cultured in hormonally defined media.

Authors:  M Salas-Prato; J F Tanguay; Y Lefebvre; D Wojciechowicz; H H Liem; D W Barnes; G Ouellette; U Muller-Eberhard
Journal:  In Vitro Cell Dev Biol       Date:  1988-03

Review 3.  Plasma protein induction by isolated hepatocytes.

Authors:  L J Crane; D L Miller
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396

4.  The relationship between cell volume, ploidy. and functional activity in differentiating hepatocytes.

Authors:  J Deschênes; J P Valet; N Marceau
Journal:  Cell Biophys       Date:  1981-12

5.  Growth state-dependent phenotypes of adult hepatocytes in primary monolayer culture.

Authors:  H Leffert; T Moran; S Sell; H Skelly; K Ibsen; M Mueller; I Arias
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

6.  Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility.

Authors:  Philippe Gabant; Lesley Forrester; Jennifer Nichols; Thierry Van Reeth; Christelle De Mees; Bernard Pajack; Alistair Watt; Johan Smitz; Henri Alexandre; Claude Szpirer; Josiane Szpirer
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-24       Impact factor: 11.205

7.  The alpha-fetoprotein (AFP) third domain: a search for AFP interaction sites of cell cycle proteins.

Authors:  G J Mizejewski
Journal:  Tumour Biol       Date:  2016-07-22

8.  Modulation of functional activities in cultured rat hepatocytes.

Authors:  C Guguen-Guillouzo; A Guillouzo
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396

9.  Estradiol-activated alpha-fetoprotein suppresses the uterotropic response to estrogens.

Authors:  G J Mizejewski; M Vonnegut; H I Jacobson
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

10.  Growth control of differentiated fetal rat hepatocytes in primary monolayer culture. IX. Specific inhibition of DNA synthesis initiation by very low density lipoprotein and possible significance to the problem of liver regeneration.

Authors:  H L Leffert; D B Weinstein
Journal:  J Cell Biol       Date:  1976-07       Impact factor: 10.539
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