| Literature DB >> 540104 |
T E Sadler, P D Jones, J E Castro, I A Lampert.
Abstract
A strain of C. parvum, CN6134, known to have antitumour activity, caused thrombosis in the sites where the organism is phagocytosed. It bound to macrophages in vitro and activated the alternate pathway of complement. A strain of C. parvum, CN5888, which fails to show antitumour activity, did not show thrombosis. It did not bind to macrophages or activate guinea-pig complement. It did, however, cause marrow infarction which seems to result from a diminished clearance of the organism from the circulation.Entities:
Mesh：
Year: 1979 PMID： 540104 PMCID： PMC2041560
Source DB: PubMed Journal: Br J Exp Pathol ISSN： 0007-1021