Literature DB >> 540062

Effect of methylamalonic acid on gluconeogenesis in isolated rat and guinea-pig hepatocytes.

I J Arinze, D Waters, M K Donaldson.   

Abstract

Gluconeogenesis from pyruvate, alanine, lactate and propionate was inhibited by methylmalonate in both rat and guinea-pig hepatocytes. The effect was dose-dependent. Gluconeogenesis from glycerol and xylitol was not affected.

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Year:  1979        PMID： 540062      PMCID： PMC1161861          DOI： 10.1042/bj1840717

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  10 in total

Review 1.  Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis.

Authors:  R W Hanson; A J Garber
Journal:  Am J Clin Nutr       Date:  1972-10       Impact factor: 7.045

2.  Inhibition of gluconeogenesis by butylmalonate in perfused rat liver.

Authors:  J R Williamson; J Anderson; E T Browning
Journal:  J Biol Chem       Date:  1970-04-10       Impact factor: 5.157

3.  The inhibition of malate, tricarboxylate and oxoglutarate entry into mitochondria by 2-n-butylmalonate.

Authors:  B H Robinson; J B Chappell
Journal:  Biochem Biophys Res Commun       Date:  1967-07-21       Impact factor: 3.575

4.  The regulation of gluconeogenesis in mammalian liver. The role of mitochondrial phosphoenolpyruvate carboxykinase.

Authors:  I J Arinze; A J Garber; R W Hanson
Journal:  J Biol Chem       Date:  1973-04-10       Impact factor: 5.157

5.  Factors affecting the kinetics and equilibrium of exchange reactions of the citrate-transporting system of rat liver mitochondria.

Authors:  B H Robinson; G R Williams; M L Halperin; C C Leznoff
Journal:  J Biol Chem       Date:  1971-09-10       Impact factor: 5.157

6.  Observations on the coexistence of methylmalonic acidemia and glycinemia.

Authors:  G Morrow; L A Barness; V H Auerbach; A M DiGeorge; T Ando; W L Nyhan
Journal:  J Pediatr       Date:  1969-05       Impact factor: 4.406

7.  Gluconeogenesis by isolated guinea-pig liver parenchymal cells.

Authors:  I J Arinze; D L Rowley
Journal:  Biochem J       Date:  1975-11       Impact factor: 3.857

8.  Methylmalonic aciduria. An inborn error of metabolism leading to chronic metabolic acidosis.

Authors:  V G Oberholzer; B Levin; E A Burgess; W F Young
Journal:  Arch Dis Child       Date:  1967-10       Impact factor: 3.791

9.  The inhibition by methylmalonic acid of malate transport by the dicarboxylate carrier in rat liver mitochondria. A possible explantation for hypoglycemia in methylmalonic aciduria.

Authors:  M L Halperin; C M Schiller; I B Fritz
Journal:  J Clin Invest       Date:  1971-11       Impact factor: 14.808

10.  Gluconeogenesis from propionate in kidney and liver of the vitamin B12-deficient rat.

Authors:  M J Weidemann; R Hems; D L Williams; G H Spray; H A Krebs
Journal:  Biochem J       Date:  1970-03       Impact factor: 3.857
  10 in total
  1 in total

1.  Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids.

Authors:  E P Brass; R A Beyerinck
Journal:  Biochem J       Date:  1988-03-15       Impact factor: 3.857
  1 in total

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