Literature DB >> 5378375

The intermediary role of a steroid 8,14-dien-3-beta-ol system in ergosterol biosynthesis.

M Akhtar, W A Brooks, I A Watkinson.   

Abstract

1. A mechanism for the removal of the 14alpha-methyl group in ergosterol biosynthesis that involves the intermediacy of an 8,14-diene system is outlined. 2. In accordance with the requirements of this scheme, it is shown that 5alpha-ergosta-8,14-dien-3beta-ol is converted into ergosterol by Saccharomyces cerevisiae.

Entities:  

Mesh：

Substances：

Year:  1969        PMID： 5378375      PMCID： PMC1185083          DOI： 10.1042/bj1150135

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  6 in total

1.  Synthesis of isomeric 4,4-dimethylcholestenols and identification of a lanosterol metabolite.

Authors:  F GAUTSCHI; K BLOCH
Journal:  J Biol Chem       Date:  1958-12       Impact factor: 5.157

2.  On the demethylation of lanosterol to cholesterol.

Authors:  J A OLSON; M LINDBERG; K BLOCH
Journal:  J Biol Chem       Date:  1957-06       Impact factor: 5.157

3.  Net synthesis of sterols in resting cells of Saccharomyces cerevisiae.

Authors:  H P KLEIN; N R EATON; J C MURPHY
Journal:  Biochim Biophys Acta       Date:  1954-04

4.  The fate of the 15-beta hydrogen of lanosterol in cholesterol biosynthesis.

Authors:  L Canonica; A Fiecchi; M G Kienle; A Scala; G Galli; E G Paoletti; R Paoletti
Journal:  J Am Chem Soc       Date:  1968-06-19       Impact factor: 15.419

5.  The role of a cholesta-8,14-dien-3-beta-ol system in cholesterol biosynthesis.

Authors:  M Akhtar; I A Watkinson; A D Rahimtula; D C Wilton; K A Munday
Journal:  Biochem J       Date:  1969-03       Impact factor: 3.857

6.  The status of C-6, C-7, C-15 and C-16 hydrogen atoms in cholesterol biosynthesis.

Authors:  M Akhtar; A D Rahimtula; I A Watkinson; D C Wilton; K A Munday
Journal:  Eur J Biochem       Date:  1969-05-01
  6 in total
  3 in total

1.  Physiological effects of an antimycotic azasterol on cultures of Saccharomyces cerevisiae.

Authors:  P R Hays; W D Neal; L W Parks
Journal:  Antimicrob Agents Chemother       Date:  1977-08       Impact factor: 5.191

2.  Mode of action of the azasteroid antibiotic 15-aza-24 methylene-d-homocholesta-8,14-dien-3 beta-ol in Ustilago maydis.

Authors:  C P Woloshuk; H D Sisler; S R Dutky
Journal:  Antimicrob Agents Chemother       Date:  1979-07       Impact factor: 5.191

Review 3.  Biochemical and physiological effects of sterol alterations in yeast--a review.

Authors:  L W Parks; S J Smith; J H Crowley
Journal:  Lipids       Date:  1995-03       Impact factor: 1.880
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.