Literature DB >> 5370096

Factors which determine the gastric secretory response to 2-deoxy-D-glucose.

R L Himsworth, D G Colin-Jones.   

Abstract

The physiological factors which determine the penetration of the brain by 2-deoxy-D-glucose have been studied and the practical importance of the blood-brain barrier has been demonstrated. The evaluation of the gastric secretory response to 2-deoxy-D-glucose has been shown to depend upon the plasma glucose concentration. It is concluded that because of the hazards and uncertainties in the use of 2-deoxy-D-glucose in man its use is to be deprecated.

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Year:  1969        PMID： 5370096      PMCID： PMC1553020          DOI： 10.1136/gut.10.12.1015

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  8 in total

1.  Increased adrenaline production following administration of 2-deoxy-D-glucose in the rat.

Authors:  B HOKFELT; S BYDGEMAN
Journal:  Proc Soc Exp Biol Med       Date:  1961-03

2.  The location of the chemoreceptor controlling gastric acid secretion during hypoglycaemia.

Authors:  R L Himsworth; D G Colin-Jones
Journal:  Clin Sci       Date:  1969-10       Impact factor: 6.124

3.  Use of 2 deoxy-D-glucose to test for the completeness of surgical vagotomy.

Authors:  D G Thomas; H L Duthie
Journal:  Gut       Date:  1968-02       Impact factor: 23.059

4.  On the critical nature of blood sugar levels in the vagal stimulation of gastric acid secretion in normal and diabetic dogs.

Authors:  D R Kemp; F Herrera; J Isaza; M M Eisenberg
Journal:  Surgery       Date:  1968-11       Impact factor: 3.982

5.  Vagal gastric secretory stimulation by 2-deoxy-D-glucose.

Authors:  B I Hirschowitz; G Sachs
Journal:  Am J Physiol       Date:  1965-09

6.  Facilitated transfer of glucose from blood into brain tissue.

Authors:  C Crone
Journal:  J Physiol       Date:  1965-11       Impact factor: 5.182

7.  Compensatory reactions to a lack of metabolizable glucose.

Authors:  R L Himsworth
Journal:  J Physiol       Date:  1968-09       Impact factor: 5.182

8.  The secretion of gastric acid in response to a lack of metabolizable glucose.

Authors:  D G Colin-Jones; R L Himsworth
Journal:  J Physiol       Date:  1969-05       Impact factor: 5.182
  8 in total
  4 in total

1.  [Inhibition of gastric acid secretion in chickens by atropine, insulin and 2-deoxy-D-glucose].

Authors:  H J Ruoff; K F Sewing
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

2.  Histamine metabolism of the guinea-pig gastric mucosa.

Authors:  J Bergmark; G Granerus; S Henningsson; L Lundell; E Rosengren
Journal:  J Physiol       Date:  1976-05       Impact factor: 5.182

3.  An assessment of the reproducibility and safety of 2-deoxy-D-glucose as a gastric acid stimulant in duodenal ulcer patients.

Authors:  A L Gough; N C Keddie
Journal:  Gut       Date:  1975-03       Impact factor: 23.059

4.  Further studies on the mode of action of isoprenaline on gastric secretion in the conscious rat.

Authors:  L Lundell; S E Svensson; G Nilsson
Journal:  Br J Pharmacol       Date:  1976-09       Impact factor: 8.739
  4 in total

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