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Literature DB >> 536934

Growth of Leishmania donovani amastigotes in a continuous macrophage-like cell culture.

Abstract

The feastibility of using a macrophage-like murine tumor cell as a host for Leishmania donovani was investigated. This cell line, designated P388D1, rapidly phagocytized amastigotes and supported their intracellular replication. It can serve as a model "host" without the inherent limitations of primary macrophage cultures.

Entities: Disease Species

Mesh：

Year: 1979 PMID： 536934 DOI： 10.1111/j.1550-7408.1979.tb04652.x

Source DB: PubMed Journal: J Protozool ISSN： 0022-3921

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Cited

7 in total

1. Promastigote infectivity in Leishmania infantum.

Authors: F Grimm; R Brun; L Jenni
Journal: Parasitol Res Date: 1991 Impact factor: 2.289

2. Use of in vitro method to assess different brands of anti-leishmanial drugs.

Authors: S K Arora; R Sinha; S Sehgal
Journal: Med Microbiol Immunol Date: 1991 Impact factor: 3.402

3. Increased myelopoiesis during Leishmania major infection in mice: generation of 'safe targets', a possible way to evade the effector immune mechanism.

Authors: A M Mirkovich; A Galelli; A C Allison; F Z Modabber
Journal: Clin Exp Immunol Date: 1986-04 Impact factor: 4.330

7. Receptor-mediated entry of beta-glucuronidase into the parasitophorous vacuoles of macrophages infected with Leishmania mexicana amazonensis.

Authors: V L Shepherd; P D Stahl; P Bernd; M Rabinovitch
Journal: J Exp Med Date: 1983-05-01 Impact factor: 14.307

7 in total

Growth of Leishmania donovani amastigotes in a continuous macrophage-like cell culture.

1. Promastigote infectivity in Leishmania infantum.

2. Use of in vitro method to assess different brands of anti-leishmanial drugs.

3. Increased myelopoiesis during Leishmania major infection in mice: generation of 'safe targets', a possible way to evade the effector immune mechanism.

4. Leishmania mexicana pifanoi: in vivo and in vitro interactions between amastigotes and macrophages.

5. Interactions between macrophagelike cells and Leishmania braziliensis in vitro.

6. Growth of Trypanosoma cruzi in a cloned macrophage cell line and in a variant defective in oxygen metabolism.

7. Receptor-mediated entry of beta-glucuronidase into the parasitophorous vacuoles of macrophages infected with Leishmania mexicana amazonensis.