Literature DB >> 536914

A method for investigating the role of calcium in the shape change, aggregation and serotonin release of rat platelets.

J S Belville, W F Bennett, G Lynch.   

Abstract

1. Effects of the platelet secretagogues thrombin and Concanavalin A (Con A) on shape change and release have been studied under conditions where external Ca2+ and ADP have been controlled. 2. In the absence of detectable aggregation both Con A- and thrombin-induced release of serotonin are markedly dependent upon extracellular calcium. 3. Con A, unlike thrombin, does not produce aggregation in calcium-supplemented medium. 4. The above property of Con A suggests that, in combination with added creatine phosphate and creatine phosphokinase, this ligand will be of value in the analysis of calcium-dependent release in platelets.

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Year:  1979        PMID： 536914      PMCID： PMC1458720          DOI： 10.1113/jphysiol.1979.sp013040

Source DB:  PubMed          Journal:  J Physiol        ISSN： 0022-3751            Impact factor:   5.182


  21 in total

1.  PLATELET SEQUESTRATION IN MAN. I. METHODS.

Authors:  R H ASTER; J H JANDL
Journal:  J Clin Invest       Date:  1964-05       Impact factor: 14.808

2.  THE AGGREGATION OF BLOOD PLATELETS.

Authors:  G V BORN; M J CROSS
Journal:  J Physiol       Date:  1963-08       Impact factor: 5.182

3.  ROLE OF PLATELET FIBRINOGEN IN THE REACTIONS OF PLATELETS TO THROMBIN.

Authors:  E E MORSE; D P JACKSON; C L CONLEY
Journal:  J Clin Invest       Date:  1965-05       Impact factor: 14.808

4.  THE INITIAL CHANGES IN PLATELET MORPHOLOGY FOLLOWING THE ADDITION OF ADENOSINE DIPHOSPHATE.

Authors:  D C MACMILLAN; M F OLIVER
Journal:  J Atheroscler Res       Date:  1965 Jul-Aug

5.  Common activation of aggregation and released reaction of platelets.

Authors:  H Patscheke; P Wörner
Journal:  Thromb Res       Date:  1977-09       Impact factor: 3.944

6.  Interactions of polylysine with platelets.

Authors:  C S Jenkins; M A Packham; R L Kinlough-Rathbone; J F Mustard
Journal:  Blood       Date:  1971-04       Impact factor: 22.113

7.  Release reaction in washed platelet suspensions induced by kaolin and other particles.

Authors:  S Cronberg; J P Caen
Journal:  Scand J Haematol       Date:  1971

8.  Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion.

Authors:  J G White; G H Rao; J M Gerrard
Journal:  Am J Pathol       Date:  1974-11       Impact factor: 4.307

9.  Observations on the change in shape of blood platelets brought about by adenosine diphosphate.

Authors:  G V Born
Journal:  J Physiol       Date:  1970-08       Impact factor: 5.182

10.  The release of nucleotides, 5-hydroxytryptamine and enzymes from human blood platelets during aggregation.

Authors:  D C Mills; I A Robb; G C Roberts
Journal:  J Physiol       Date:  1968-04       Impact factor: 5.182
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  3 in total

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Journal:  J Physiol       Date:  2002-11-01       Impact factor: 5.182

2.  Helicobacter pylori urease activates blood platelets through a lipoxygenase-mediated pathway.

Authors:  German E Wassermann; Deiber Olivera-Severo; Augusto F Uberti; Célia R Carlini
Journal:  J Cell Mol Med       Date:  2009-09-14       Impact factor: 5.310

3.  The role of the PLR-NLR combination in the prediction of the presence of Helicobacter pylori and its associated complications.

Authors:  Mustafa Kaplan; Ihsan Ates; Mahmut Yuksel; Mehmet F Arikan; Gulden Aydog; Nesrin Turhan; Volkan Gökbulut; Ertugrul Kayacetin
Journal:  Saudi J Gastroenterol       Date:  2018 Sep-Oct       Impact factor: 2.485
  3 in total

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