Literature DB >> 536463

Liver damage due to perhexiline maleate.

G B Forbes, M O Rake, D J Taylor.   

Abstract

Two middle-aged men, who had received perhexiline in recommended dosage, showed clinical and histological evidence of severe hepatic damage, and one of them died. Histological study of the livers showed a striking resemblance to alcoholic hepatitis.

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Year:  1979        PMID： 536463      PMCID： PMC1145951          DOI： 10.1136/jcp.32.12.1282

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  7 in total

1.  [Letter: Subacute toxic hepatitis following perhexiline maleate therapy].

Authors:  M Pelletier; R Lambert; P Paliard; R Bory
Journal:  Nouv Presse Med       Date:  1976-04-17

2.  Perhexiline maleate-induced cirrhosis.

Authors:  D Pessayre; M Bichara; C Degott; F Potet; J P Benhamou; G Feldmann
Journal:  Gastroenterology       Date:  1979-01       Impact factor: 22.682

3.  Report of a multicentre monitored release study of perhexiline maleate in the prevention of angina pectoris.

Authors:  J D Lockhart; H C Masheter
Journal:  Br J Clin Pract       Date:  1976-09

4.  Liver damage after perhexiline maleate.

Authors:  G S McDonald
Journal:  Lancet       Date:  1977-05-14       Impact factor: 79.321

5.  [Liver cirrhosis after 2 years of perhexiline maleate treatment].

Authors:  P Bonnet; J Jourdan; F Janbon; H Michel; A Bertrand
Journal:  Nouv Presse Med       Date:  1978-01-21

6.  [Hepatitis due to perhexiline maleate. Development of cirrhosis after interruption of the drug. Report of two cases (author's transl)].

Authors:  M Beaugrand; M Chousterman; P Callard; J P Camilleri; J Petite; J P Ferrier
Journal:  Gastroenterol Clin Biol       Date:  1977-10

7.  Liver damage associated with perhexiline maleate.

Authors:  D Lewis; H C Wainwright; M C Kew; S Zwi; C Isaacson
Journal:  Gut       Date:  1979-03       Impact factor: 23.059
  7 in total
  5 in total

1.  "Nonalcoholic steatohepatitis" induced by massive doses of synthetic estrogen.

Authors:  K Seki; Y Minami; M Nishikawa; S Kawata; S Miyoshi; Y Imai; S Tarui
Journal:  Gastroenterol Jpn       Date:  1983-06

2.  Polymorphic hydroxylation of perhexiline maleate in man.

Authors:  R G Cooper; D A Evans; E J Whibley
Journal:  J Med Genet       Date:  1984-02       Impact factor: 6.318

3.  Polymorphic hydroxylation of perhexiline in vitro.

Authors:  L B Sørensen; R N Sørensen; J O Miners; A A Somogyi; N Grgurinovich; D J Birkett
Journal:  Br J Clin Pharmacol       Date:  2003-06       Impact factor: 4.335

4.  Impaired oxidation of debrisoquine in patients with perhexiline liver injury.

Authors:  M Y Morgan; R Reshef; R R Shah; N S Oates; R L Smith; S Sherlock
Journal:  Gut       Date:  1984-10       Impact factor: 23.059

Review 5.  Drug effects on the liver. An updated tabular compilation of drugs and drug-related hepatic diseases.

Authors:  J Ludwig; R Axelsen
Journal:  Dig Dis Sci       Date:  1983-07       Impact factor: 3.199
  5 in total

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