Relationship of platelet retention in glass bead columns to the rate of aggregation with adenosine diphosphate and thrombin.

The initial rate of platelet aggregation induced by adenosine diphosphate and thrombin correlated with the number of platelets retained when samples of citrated blood from the same normal donors were passed through glass bead columns. The results support the view that the glass bead column method of measuring platelet ;adhesiveness' is influenced by platelet aggregation.