Literature DB >> 5360590

Antibodies to polynucleotides: distribution in human serums.

D Koffler, R I Carr, V Agnello, T Fiezi, H G Kunkel.   

Abstract

Hemagglutination procedures were used to determine the distribution of antibodies to native DNA, single-stranded DNA, and double-stranded RNA. Antibodies to all three polynucleotides were found in a high percentage of the serums of patients with systemic lupus erythematosus. Antibodies to native DNA occurred almost exclusively in serums of patients in the active stages of systemic lupus erythematosus, whereas antibodies to single-stranded DNA were observed in the serums of patients with several diseases and of some normal individuals.

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Year:  1969        PMID： 5360590     DOI： 10.1126/science.166.3913.1648

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  36 in total

1.  Disease activity in the nephritis of systemic lupus erythematosus in relation to serum complement concentrations. DNA-binding capacity and precipitating anti-DNA antibody.

Authors:  J S Cameron; M H Lessof; C S Ogg; B D Williams; D G Williams
Journal:  Clin Exp Immunol       Date:  1976-09       Impact factor: 4.330

Review 2.  B-cell epitopes of RNA autoantigens.

Authors:  R M Hoet; W J van Venrooij
Journal:  Mol Biol Rep       Date:  1992-06       Impact factor: 2.316

3.  Lack of specificity for antibodies to double stranded DNA found in four commercial kits.

Authors:  M Kadlubowski; M Jackson; P L Yap; G Neill
Journal:  J Clin Pathol       Date:  1991-03       Impact factor: 3.411

4.  Immunological detection of nucleic acids and antibodies to nucleic acids and nuclear antigens by counterimmunoelectrophoresis.

Authors:  P H Schur; D DeAngelis; J M Jackson
Journal:  Clin Exp Immunol       Date:  1974-05       Impact factor: 4.330

5.  Studies on drug induced lupus erythematosus in mice. I. Drug induced antinuclear antibodies (ANA).

Authors:  J H ten Veen; T E Feltkamp
Journal:  Clin Exp Immunol       Date:  1972-06       Impact factor: 4.330

6.  Studies on drug-induced lupus erythematosus in mice. 3. Renal lesions and splenomegaly in drug-induced lupus erythematosus.

Authors:  T M Feltkamp-Vroom
Journal:  Clin Exp Immunol       Date:  1973-12       Impact factor: 4.330

7.  Measurement of serum DNA binding in chronic active hepatitis and systemic lupus erythematosus using the Farr assay.

Authors:  K M Pollard; R Steele; S Hogg; J Webb
Journal:  Rheumatol Int       Date:  1986       Impact factor: 2.631

8.  Determination of anti-DNA antibodies by a modified 125I-labelled DNA-binding test. Elimination of non-specific binding of DNA to non-immunoglobulin basic proteins by using an anionic detergent.

Authors:  S Izui; P H Lambert; P A Miescher
Journal:  Clin Exp Immunol       Date:  1976-12       Impact factor: 4.330

Review 9.  Clinical significance of antibodies to double stranded DNA (dsDNA) for systemic lupus erythematosus (SLE).

Authors:  T Swaak; R Smeenk
Journal:  Clin Rheumatol       Date:  1987-06       Impact factor: 2.980

10.  The occurrence of antibodies against single-stranded DNA in the sera of patients with acute and chronic leukaemia.

Authors:  S Izui; P H Lambert; N Carpentier; P A Miescher
Journal:  Clin Exp Immunol       Date:  1976-06       Impact factor: 4.330
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