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Literature DB >> 5359943

Assessment of platelet production with 75Se selenomethionine.

Abstract

Incorporation of intravenously injected (75)Se selenomethionine into platelets has been found to vary with alterations in the rate of platelet production. It appears to label newly produced platelets during their formation in megakaryocytes and provides a method by which thrombopoiesis may be studied in vivo. This technique may be applicable to clinical studies of disordered platelet production.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1969 PMID： 5359943 PMCID： PMC1630288 DOI： 10.1136/bmj.4.5686.782

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

10 in total

1. TWO MECHANISMS OF SULFATE-S35 UPTAKE BY BLOOD PLATELETS OF RATS.

Authors: T T ODELL; T P MCDONALD
Journal: Am J Physiol Date: 1964-03

2. Uptake of radioactive sulfate by elements of the blood and the bone marrow of rats.

Authors: T T ODELL; F G TAUSCHE; W D GUDE
Journal: Am J Physiol Date: 1955-03

Review 3. Newer tracer techniques in hematology.

Authors: P A McIntyre; H N Wagner
Journal: Prog Hematol Date: 1969

4. Kinetics of thrombopoiesis.

Authors: L A Harker
Journal: J Clin Invest Date: 1968-03 Impact factor: 14.808

5. The turnover of [75Se] selenomethionine in infants and rats measured in a whole body counter.

Authors: J C Waterlow; J S Garrow; D J Millward
Journal: Clin Sci Date: 1969-06 Impact factor: 6.124

6. Platelet counts with the Coulter counter.

Authors: B S Bull; M A Schneiderman; G Brecher
Journal: Am J Clin Pathol Date: 1965-12 Impact factor: 2.493

7. The interconversion and reutilization of injected 75-Se-selenomethionine in the rat.

Authors: H K Awwad; S J Adelstein; E J Potchen; J B Dealy
Journal: J Biol Chem Date: 1967-02-10 Impact factor: 5.157

8. Investigation of erythrocyte turnover with selenium-75-labeled methionine.

Authors: J A Penner
Journal: J Lab Clin Med Date: 1966-03

9. The regional distribution of Se75-selenomethionine in the rat.

Authors: H K Awwad; E J Potchen; S J Adelstein; J B Dealy
Journal: Metabolism Date: 1966-04 Impact factor: 8.694

10. Physiology of the regulation of platelet production.

Authors: G De Gabriele; D G Penington
Journal: Br J Haematol Date: 1967-03 Impact factor: 6.998