| Literature DB >> 5350331 |
S Spector, J H Fleisch, H M Maling, B B Brodie.
Abstract
Aortic strips from spontaneously hypertensive rats were less responsive than normal animals to the contractile effects of norepinephrine, serotonin, and potassium chloride but more reactive to the relaxant effects of the stimulant of beta receptors, isoproterenol. Thus, hypertension is not the result of an absence of beta receptor or a hypersensitivity of the vascular smooth muscle.Entities:
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Year: 1969 PMID: 5350331 DOI: 10.1126/science.166.3910.1300
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728