Literature DB >> 5350319

Corticosterone regulation of tryptophan hydroxylase in midbrain of the rat.

E C Azmitia, B S McEwen.   

Abstract

The tryptophan hydroxylase activity in the rat midbrain decreases after adrenalectomy and is restored by treatment with corticosterone. Cycloheximide, adminiistered intracisternally, prevents the restoration of the enzyme activity by corticosterone. Cycloheximide administration to adrenalectomized rats resutlts in a further decrease in the enzyme activity. an indication that the enzyme has a rapid turnover even in the absence of corticosterone.

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Year:  1969        PMID： 5350319     DOI： 10.1126/science.166.3910.1274

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Hormonal imputs and brain tryptophan metabolism: the effect of growth hormone.

Authors:  D Cocchi; A di Giulio; A Groppetti; P Mantegazza; E E Müller; P F Spano
Journal:  Experientia       Date:  1975-03-15

2.  Enzyme activity changes relevant to the control of tryptophan metabolism.

Authors:  G Curzon
Journal:  Biochem J       Date:  1972-11       Impact factor: 3.857

3.  Influence of corticosterone on serotonin metabolism in rat brain.

Authors:  G L Kovacs; G Telegdy
Journal:  Neurosci Behav Physiol       Date:  1980 May-Jun

4.  Estimation of the rate of 5-HT synthesis in the mouse brain by various methods.

Authors:  Y Morot-Gaudry; M Hamon; S Bourgoin; J P Ley; J Glowinski
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

5.  5-HT1A receptor agonist reverses adrenalectomy-induced loss of granule neuronal morphology in the rat dentate gyrus.

Authors:  J Huang; J A Strafaci; E C Azmitia
Journal:  Neurochem Res       Date:  1997-11       Impact factor: 3.996

6.  Adrenocorticoids control 5-hydroxytryptamine metabolism in rat brain.

Authors:  R B Rastogi; R L Singhal
Journal:  J Neural Transm       Date:  1978       Impact factor: 3.575

7.  Involvement of oxidoreductive reactions of intracellular haemoglobin in the metabolism of 3-hydroxyanthranilic acid in human erythrocytes.

Authors:  A Tomoda; E Shirasawa; S Nagao; M Minami; Y Yoneyama
Journal:  Biochem J       Date:  1984-09-15       Impact factor: 3.857

8.  Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57/Bl6 mice.

Authors:  J A Clark; R B Flick; L-Y Pai; I Szalayova; S Key; R K Conley; A Y Deutch; P H Hutson; E Mezey
Journal:  Mol Psychiatry       Date:  2007-07-10       Impact factor: 15.992

9.  Synergistic effects of dehydroepiandrosterone and fluoxetine on proliferation of progenitor cells in the dentate gyrus of the adult male rat.

Authors:  S B Pinnock; S E Lazic; H T Wong; I H W Wong; J Herbert
Journal:  Neuroscience       Date:  2008-10-30       Impact factor: 3.590

10.  Chronic citalopram administration causes a sustained suppression of serotonin synthesis in the mouse forebrain.

Authors:  Gerard Honig; Minke E Jongsma; Marieke C G van der Hart; Laurence H Tecott
Journal:  PLoS One       Date:  2009-08-27       Impact factor: 3.240
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