| Literature DB >> 5350039 |
Abstract
A method is described for isolation of the acid-hydrolysable metabolite of aldosterone in sufficient purity to measure accurately the daily production rate. Values obtained with six hospital patients were 84-131mug./day on a daily intake of 100m-equiv. of Na(+) and 227-464mug./day on a daily intake of 10m-equiv. of Na(+). Corresponding values for aldosterone excretion were also recorded, but these are a poor index of production rate since they represent from 1.6 to 9.8% of the total daily output of aldosterone.Entities:
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Year: 1969 PMID: 5350039 PMCID: PMC1185075 DOI: 10.1042/bj1150109
Source DB: PubMed Journal: Biochem J ISSN: 0264-6021 Impact factor: 3.857