Literature DB >> 5349284

Metyrapone interaction with hepatic microsomal cytochrome P-450 from rats treated with phenobarbital.

A G Hildebrandt, K C Leibman, R W Estabrook.   

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Year:  1969        PMID： 5349284     DOI： 10.1016/0006-291x(69)90940-1

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


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  16 in total

1.  Non-competitive and competitive inhibition of mixed function oxidase in rat liver microsomes by metyrapone.

Authors:  I Roots; A G Hildebrandt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

2.  Action of metyrapone on the redox state of free nicotinamide-adenine dinucleotide and on oxygen consumption of perfused rat livers and isolated mitochondria.

Authors:  G F Kahl; S Simon
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1971

3.  Active centers of microsomal cytochrome P-450 determined with metyrapone by mutural depletion system kinetics.

Authors:  I Roots; A G Hildebrandt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

4.  Experiments on the metyrapone reducing microsomal enzyme system.

Authors:  G F Kahl
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1970

5.  Species of cytochrome P-450 in rat liver microsomes with different stereoselectivity for the binding and monooxygenation of (+)- and (-)-methylphenobarbital.

Authors:  W Bohn; V Ullrich; H Staudinger
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1971

6.  Competitive inhibition of the microsomal n-hydroxylation of 4-chloroaniline by metyrapone and cyclohexane.

Authors:  H Uehleke; K H Hellmer
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1971

7.  The mechanism of halothane binding to microsomal cytochrome P450.

Authors:  D Mansuy; W Nastainczyk; V Ullrich
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

8.  The binding of metyrapone to cytochrome P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions.

Authors:  A G Hildebrandt
Journal:  Biochem J       Date:  1971-11       Impact factor: 3.857

9.  Multiple forms of cytochrome P450 in the microsomal monooxygenase system.

Authors:  V Ullrich; P Kremers
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

10.  Evidence that ligand formation is a mechanism underlying the maintenance of cytochrome P-450 in rat liver cell culture. Potent maintenance by metyrapone.

Authors:  A J Paine; P Villa; L J Hockin
Journal:  Biochem J       Date:  1980-06-15       Impact factor: 3.857
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