Literature DB >> 5348474

Carbon tetrachloride metabolism in the rabbit.

J S Fowler.   

Abstract

1. Carbon tetrachloride was administered by stomach tube to rabbits and its distribution in fat, liver, kidney and muscle studied by gas liquid chromatography, during the next 48 hr.2. Chloroform, hexachloroethane and two unidentified chlorinated metabolites were detected in the tissues.3. Hexachloroethane may arise by dimerization of free trichloromethyl radicals.

Entities:  

Mesh：

Substances：

Year:  1969        PMID： 5348474      PMCID： PMC1703718          DOI： 10.1111/j.1476-5381.1969.tb08512.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  4 in total

1.  Reduction of carbon tetrachloride in vivo and reduction of carbon tetrachloride and chloroform in vitro by tissues and tissue constituents.

Authors:  T C BUTLER
Journal:  J Pharmacol Exp Ther       Date:  1961-12       Impact factor: 4.030

2.  Increased susceptibility to carbon tetrachloride poisoning in the rat after pretreatment with oral phenobarbitone.

Authors:  R C Garner; A E McLean
Journal:  Biochem Pharmacol       Date:  1969-03       Impact factor: 5.858

3.  Lipid metabolites of carbon tetrachloride.

Authors:  E Gordis
Journal:  J Clin Invest       Date:  1969-01       Impact factor: 14.808

4.  Some hepatotoxic actions of hexachloroethane and its metabolites in sheep.

Authors:  J S Fowler
Journal:  Br J Pharmacol       Date:  1969-03       Impact factor: 8.739
  4 in total
  10 in total

1.  The antihepatotoxic activity of dithiocarb as compared with six other thio compounds in mice.

Authors:  C P Siegers; O Strubelt; M Völpel
Journal:  Arch Toxicol       Date:  1978-10-13       Impact factor: 5.153

2.  Pollution due to volatile halocarbon compounds in biota.

Authors:  M Gotoh; Y Sekitani; T Aramaki; H Kobayashi; K Ogino; T Hobara
Journal:  Bull Environ Contam Toxicol       Date:  1992-08       Impact factor: 2.151

3.  [Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450].

Authors:  O Reiner; S Athanassopoulos; K H Hellmer; R E Murray; H Uehleke
Journal:  Arch Toxikol       Date:  1972

Review 4.  Free-radical mechanisms in tissue injury.

Authors:  T F Slater
Journal:  Biochem J       Date:  1984-08-15       Impact factor: 3.857

5.  Quercetin prevents oxidative stress in cirrhotic rats.

Authors:  Pavanato Maria Amália; Marroni Norma Possa; Marroni Claúdio Augusto; Llesuy Susana Francisca
Journal:  Dig Dis Sci       Date:  2007-04-12       Impact factor: 3.199

6.  Carbon tetrachloride metabolism in sheep and in Fasciola hepatica.

Authors:  J S Fowler
Journal:  Br J Pharmacol       Date:  1970-07       Impact factor: 8.739

7.  Relationship of oxygen and glutathione in protection against carbon tetrachloride-induced hepatic microsomal lipid peroxidation and covalent binding in the rat. Rationale for the use of hyperbaric oxygen to treat carbon tetrachloride ingestion.

Authors:  R F Burk; J M Lane; K Patel
Journal:  J Clin Invest       Date:  1984-12       Impact factor: 14.808

8.  Carbon tetrachloride-induced liver injury in the rabbit.

Authors:  A S Bernacchi; C R de Castro; E C de Ferreyra; M C Villarruel; G Fernández; O M de Fenos; J A Castro
Journal:  Br J Exp Pathol       Date:  1983-06

Review 9.  Biochemical studies on the metabolic activation of halogenated alkanes.

Authors:  K H Cheeseman; E F Albano; A Tomasi; T F Slater
Journal:  Environ Health Perspect       Date:  1985-12       Impact factor: 9.031

10.  Model studies in cytochrome P-450-mediated toxicity of halogenated compounds: radical processes involving iron porphyrins.

Authors:  D Brault
Journal:  Environ Health Perspect       Date:  1985-12       Impact factor: 9.031
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.