Literature DB >> 5348470

Sodium-dependent accumulation of 5-hydroxytryptamine by rat blood platelets.

J M Sneddon.   

Abstract

1. The influence of sodium and potassium on the accumulation of 5-hydroxytryptamine (5-HT) by rat blood platelets was investigated.2. An absolute dependence of 5-HT uptake on the sodium concentration in the medium was found.3. Removal of potassium reduced the uptake by about 60%. High concentrations of potassium inhibited sodium-dependent accumulation.4. The observations have been discussed in terms of a carrier-mediated transport process for 5-HT operating in the platelet membrane.

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Year:  1969        PMID： 5348470      PMCID： PMC1703717          DOI： 10.1111/j.1476-5381.1969.tb08506.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  22 in total

1.  TRANSPORT OF GLYCINE BY PIGEON RED CELLS.

Authors:  G A VIDAVER
Journal:  Biochemistry       Date:  1964-05       Impact factor: 3.162

2.  The mechanism of serotonin and catecholamine uptake by platelets.

Authors:  F B HUGHES; B B BRODIE
Journal:  J Pharmacol Exp Ther       Date:  1959-10       Impact factor: 4.030

3.  Concentrative uptake of amino acids by erythrocytes in vitro.

Authors:  H N CHRISTENSEN; T R RIGGS; N E RAY
Journal:  J Biol Chem       Date:  1952-01       Impact factor: 5.157

Review 4.  Metabolism, transfer and storage of 5-hydroxytryptamine in blood platelets.

Authors:  A Pletscher
Journal:  Br J Pharmacol Chemother       Date:  1968-01

5.  Effect of drugs and cations on ultrastructure and 5-hydroxytryptamine content of blood platelets.

Authors:  M da Prada; J P Tranzer; A Pletscher
Journal:  J Pharmacol Exp Ther       Date:  1967-12       Impact factor: 4.030

Review 6.  Transport through biological membranes.

Authors:  E Heinz
Journal:  Annu Rev Physiol       Date:  1967       Impact factor: 19.318

7.  Role of Na+ and K+ on sugar (2-deoxyglucose) and amino acid (alpha-aminoisobutyric acid) transport in striated muscle.

Authors:  D M Kipnis; J E Parrish
Journal:  Fed Proc       Date:  1965 Sep-Oct

8.  Na+ -dependent transport in the intestine and other animal tissues.

Authors:  R K Crane
Journal:  Fed Proc       Date:  1965 Sep-Oct

9.  The effect of 5-hydroxytryptamine on the potassium exchange of human platelets.

Authors:  G V Born
Journal:  J Physiol       Date:  1967-05       Impact factor: 5.182

10.  Absorption of serotonin (5-hydroxytryptamine) and histamine by dog platelets.

Authors:  J H HUMPHREY; C C TOH
Journal:  J Physiol       Date:  1954-05-28       Impact factor: 5.182
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  27 in total

Review 1.  Role of transmitter uptake mechanisms in synaptic neurotransmission.

Authors:  L L Iversen
Journal:  Br J Pharmacol       Date:  1971-04       Impact factor: 8.739

2.  Effect of selective proteolysis on the accumulation of 5-hydroxytryptamine by intact rat blood platelets.

Authors:  J M Sneddon; K I Williams
Journal:  Br J Pharmacol       Date:  1974-10       Impact factor: 8.739

3.  Uptake of 5-hydroxytryptamine by domestic fowl thrombocytes (spindle cells) in vitro.

Authors:  M Sorimachi; K Kataoka; A Inouye
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

4.  Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor.

Authors:  V Claassen; J E Davies; G Hertting; P Placheta
Journal:  Br J Pharmacol       Date:  1977-08       Impact factor: 8.739

5.  The effects of adrenaline injections on human platelet monoamine oxidase and related measures.

Authors:  V Gentil; R L McCurdy; B Alevizos; M H Lader
Journal:  Psychopharmacology (Berl)       Date:  1976-11-10       Impact factor: 4.530

6.  Increased uptake of serotonin by blood platelets from patients with bipolar primary affective disorder-bipolar type.

Authors:  Z Zemishlany; H Munitz; A Rotman; H Wijsenbeek
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

7.  Uptake of 14C-5-hydroxytryptamine by human and rat platelets and its pharmacological inhibition. A comparative kinetic analysis.

Authors:  M Wielosz; M Salmona; G de Gaetano; S Garattini
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976-12       Impact factor: 3.000

8.  The two Na+ sites in the human serotonin transporter play distinct roles in the ion coupling and electrogenicity of transport.

Authors:  Bruce Felts; Akula Bala Pramod; Walter Sandtner; Nathan Burbach; Simon Bulling; Harald H Sitte; L Keith Henry
Journal:  J Biol Chem       Date:  2013-11-29       Impact factor: 5.157

9.  Short-term lithium administration to healthy volunteers produces long-lasting pronounced changes in platelet serotonin uptake but not imipramine binding.

Authors:  M F Poirier; A M Galzin; C Pimoule; H Schoemaker; K H Le Quan Bui; P Meyer; C Gay; H Loo; S Z Langer
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

10.  On the pharmacology and biochemistry of the amine-uptake mechanism in human blood platelets.

Authors:  I C Campbell; A Todrick
Journal:  Br J Pharmacol       Date:  1973-10       Impact factor: 8.739
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