Literature DB >> 534486

Comparison of radioactive peptides obtained from specifically labelled human renal and placental alkaline phosphatases.

K B Whitaker, D W Moss.   

Abstract

Peptides with different chromatographic and electrophoretic properties were obtained from human placental and renal alkaline phosphatases by tryptic digestion of the enzymes labelled with radioactive orthophosphate at their active centres. These results provide structural evidence for the distinct genetic origins of the two isoenzymes that had previously been inferred from their different properties and from the observed phenotypic variation of placental phosphatase.

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Year:  1979        PMID: 534486      PMCID: PMC1161492          DOI: 10.1042/bj1830189

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  22 in total

1.  Human organ alkaline phosphatases: discrimination by several means including starch gel electrophoresis of antienzyme-enzyme supernatant fluids.

Authors:  S H BOYER
Journal:  Ann N Y Acad Sci       Date:  1963-05-08       Impact factor: 5.691

2.  THE AMINO ACID SEQUENCE AROUND THE REACTIVE SERINE IN CALF-INTESTINAL ALKALINE PHOSPHATASE.

Authors:  L ENGSTROEM
Journal:  Biochim Biophys Acta       Date:  1964-10-23

3.  Studies on calf-intestinal alkaline phosphatase. II. Incorporation of inorganic phosphate into a highly purified enzyme preparation.

Authors:  L ENGSTROM
Journal:  Biochim Biophys Acta       Date:  1961-09-02

4.  Phosphate incorporation into alkaline phosphatase of E. coli.

Authors:  J H SCHWARTZ; F LIPMANN
Journal:  Proc Natl Acad Sci U S A       Date:  1961-12-15       Impact factor: 11.205

5.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

6.  Titration of human placental alkaline phosphatase with radioactive orthophosphate.

Authors:  K B Whitaker; D W Moss
Journal:  Clin Chim Acta       Date:  1976-09-06       Impact factor: 3.786

7.  An estimate of the catalytic-centre activity and purity of human alkaline phosphatase preparations.

Authors:  D W Moss; R H Eaton; P B Scutt
Journal:  Biochim Biophys Acta       Date:  1968-04-09

8.  Human alkaline phosphatases. I. Purification and some structural properties of the enzyme from human liver.

Authors:  K D Gerbitz; H J Kolb; O H Wieland
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1977-04

9.  The catalytic-centre activity and kinetic properties of bovine milk alkaline phosphatase.

Authors:  T E Barman; H Gutfreund
Journal:  Biochem J       Date:  1966-11       Impact factor: 3.857

10.  Partial purification of human intestinal alkaline phosphatase with affinity chromotography. Some properties and interaction of concanavalin A with alkaline phosphatase.

Authors:  T Komoda; Y Sakagishi
Journal:  Biochim Biophys Acta       Date:  1976-10-11
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  1 in total

1.  Characterization of human foetal intestinal alkaline phosphatase. Comparison with the isoenzymes from the adult intestine and human tumour cell lines.

Authors:  C M Behrens; C A Enns; H H Sussman
Journal:  Biochem J       Date:  1983-06-01       Impact factor: 3.857

  1 in total

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