Literature DB >> 5344122

Reaction of chloroacetamide with the sulfhydryl group of papain.

I M Chaiken, E L Smith.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1969        PMID： 5344122

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


× No keyword cloud information.
  7 in total

1.  Effects of conformational selectivity and of overlapping kinetically influential ionizations on the characteristics of pH-dependent enzyme kinetics. Implications of free-enzyme pKa variability in reactions of papain for its catalytic mechanism.

Authors:  K Brocklehurst; S J Willenbrock; E Salih
Journal:  Biochem J       Date:  1983-06-01       Impact factor: 3.857

2.  Biochemical characterization of the arginine-specific proteases of Porphyromonas gingivalis W50 suggests a common precursor.

Authors:  M Rangarajan; S J Smith; S U; M A Curtis
Journal:  Biochem J       Date:  1997-05-01       Impact factor: 3.857

3.  Evidence for a close similarity in the catalytic sites of papain and ficin in near-neutral media despite differences in acidic and alkaline media. Kinetics of the reactions of papain and ficin with chloroacetate.

Authors:  K Brocklehurst; S M Mushiri; G Patel; F Willenbrock
Journal:  Biochem J       Date:  1982-01-01       Impact factor: 3.857

4.  Mechanism of the reaction of papain with substrate-derived diazomethyl ketones. Implications for the difference in site specificity of halomethyl ketones for serine proteinases and cysteine proteinases and for stereoelectronic requirements in the papain catalytic mechanism.

Authors:  K Brocklehurst; J P Malthouse
Journal:  Biochem J       Date:  1978-11-01       Impact factor: 3.857

5.  Investigation of the active site of papain with fluorescent probes.

Authors:  G Allen; G Lowe
Journal:  Biochem J       Date:  1973-08       Impact factor: 3.857

6.  Chemical evidence for the pH-dependent control of ion-pair geometry in cathepsin B. Benzofuroxan as a reactivity probe sensitive to differences in the mutual disposition of the thiolate and imidazolium components of cysteine proteinase catalytic sites.

Authors:  F Willenbrock; K Brocklehurst
Journal:  Biochem J       Date:  1986-08-15       Impact factor: 3.857

7.  Consequences of molecular recognition in the S1-S2 intersubsite region of papain for catalytic-site chemistry. Change in pH-dependence characteristics and generation of an inverse solvent kinetic isotope effect by introduction of a P1-P2 amide bond into a two-protonic-state reactivity probe.

Authors:  K Brocklehurst; D Kowlessur; G Patel; W Templeton; K Quigley; E W Thomas; C W Wharton; F Willenbrock; R J Szawelski
Journal:  Biochem J       Date:  1988-03-15       Impact factor: 3.857
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.