Literature DB >> 534117

Microcirculation and blood volume in rats before and after spinal cord injury.

J Seifert, G Lob, J Probst, W Brendel.   

Abstract

Blood flow, cardiac output, blood pressure, indicator mixing time and blood volume were measured in rats before and after spinal cord injury. After cutting off the spinal cord blood flow decreases markedly in the paraplegic area but also in the main organs of the animals. Only the blood supply of the lung increases by this manipulation. As blood volume and the blood pressure is decreased and the indicator mixing time delayed the situation of the spinal cord injury can be compared with the situation after acute blood loss. Therefore it is proposed to include circulatory disturbances into the conception of the acute spinal shock situation.

Entities:  

Mesh:

Year:  1979        PMID: 534117     DOI: 10.1038/sc.1979.85

Source DB:  PubMed          Journal:  Paraplegia        ISSN: 0031-1758


  3 in total

1.  Cephalosporin penetration into soft tissue of paralyzed limbs.

Authors:  R Darouiche; D Musher; R Hamill; C Ou; C Rognerud
Journal:  Antimicrob Agents Chemother       Date:  1989-08       Impact factor: 5.191

2.  Timeline of Changes in Biomarkers Associated with Spinal Cord Injury-Induced Polyuria.

Authors:  Jason H Gumbel; Cui Bo Yang; Charles H Hubscher
Journal:  Neurotrauma Rep       Date:  2021-10-27

3.  Longitudinal Impact of Acute Spinal Cord Injury on Clinical Pharmacokinetics of Riluzole, a Potential Neuroprotective Agent.

Authors:  Ashley Nguyen; Diana S-L Chow; Lei Wu; Yang Angela Teng; Mahua Sarkar; Elizabeth G Toups; James S Harrop; Karl M Schmitt; Michele M Johnson; James D Guest; Bizhan Aarabi; Christopher I Shaffrey; Maxwell Boakye; Ralph F Frankowski; Michael G Fehlings; Robert G Grossman
Journal:  J Clin Pharmacol       Date:  2021-07-09       Impact factor: 3.126

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.