| Literature DB >> 5328677 |
Abstract
Fructose-1 ,6-diphosphate is a feedback inhibitor of the catabolic enzyme, glycerol kinase, in Escherichia coli. A mutant was isolated which produced a desensitized enzyme. Glucose was no longer as effective in preventing the utilization of exogenous glycerol by cells which synthesized constitutively such an altered enzyme, even though the usual degree of catabolite repression still operated.Entities:
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Year: 1966 PMID: 5328677 DOI: 10.1126/science.153.3737.755
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728