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Literature DB >> 53265

Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse.

H Wagner, D Götze, L Ptschelinzew, M Röllinghoff.

Abstract

Determinants controlled by the I region of the murine H-2 complex provoked the generation of cytotoxic T lymphocytes (CTL) in both a secondary and primary mixed lymphocyte culture. The stimulating determinants appeared to be controlled by loci within the I-A subregion. The target antigens of the CTL generated were present on both lipopolysaccharide- and concanavalin-induced blast lymphocytes, but were barely detectable on phytohemagglutinin-induced blast cells. The stimulating capacity for CTL induction of a complete H-2 complex incompatibility by far exceeded the sum of H-2D/K-region and I-region incompatibility, respectively.

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Year: 1975 PMID： 53265 PMCID： PMC2190067 DOI： 10.1084/jem.142.6.1477

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

29 in total

1. The specificty and the activation mechanism of cell-mediated lympholysis (CML) in man.

Authors: V P Eijsvoogel; M J du Bois; A Meinesz; A Bierhorst-Eijlander; W P Zeylemaker; P T Schellekens
Journal: Transplant Proc Date: 1973-12 Impact factor: 1.066

2. Demonstration by MLR test of a previously unsuspected intra-H-2 crossover in the B10.HTT strain: implications concerning location of MLR determinants in the Ir region.

Authors: T Meo; C S David; M Nabholz; V Miggiano; D C Shreffler
Journal: Transplant Proc Date: 1973-12 Impact factor: 1.066

Review 3. T-cell mediated immunity in vitro: an analysis of antigen recognition and target cell lysis.

Authors: M Feldman; I R Cohen; H Wekerle
Journal: Transplant Rev Date: 1972

Review 4. Allograft response in vitro.

Authors: P Häyry; L C Andersson; S Nordling; M Virolainen
Journal: Transplant Rev Date: 1972

Review 5. Cell-mediated cytotoxicity, allograft rejection, and tumor immunity.

Authors: J C Cerottini; K T Brunner
Journal: Adv Immunol Date: 1974 Impact factor: 3.543

Review 6. T-cell-mediated immune responses induced in vitro: a probe for allograft and tumor immunity.

Authors: H Wagner; M Röllinghoff; G J Nossal
Journal: Transplant Rev Date: 1973

7. Genetic control of cell-mediated lympholysis in mouse.

Authors: D J Schendel; F H Bach
Journal: J Exp Med Date: 1974-12-01 Impact factor: 14.307

8. I-region genes are expressed on T and B lymphocytes. Studies of the mixed lymphocyte reaction (MLR).

Authors: P Lonai; H O McDevitt
Journal: J Exp Med Date: 1974-11-01 Impact factor: 14.307

9. Serologic evidence for antigens controlled by the Ir region in mice.

Authors: D Götze; R A Reisfeld; J Klein
Journal: J Exp Med Date: 1973-10-01 Impact factor: 14.307

10. Role of H-2 lymphocyte-defined and serologically-defined components in the generation of cytotoxic lymphocytes.

Authors: B J Alter; F H Bach
Journal: J Exp Med Date: 1974-11-01 Impact factor: 14.307

32 in total

Review 1. Antigen-major histocompatibility complex-T cell receptors: inquiries into the immunological ménage à trois.

Authors: J Klein
Journal: Immunol Res Date: 1986 Impact factor: 2.829

2. Cytolytic thymus-derived lymphocytes specific for allogeneic stimulator cells crossreact with chemically modified syngeneic cells.

Authors:
Journal: Proc Natl Acad Sci U S A Date: 1977-03 Impact factor: 11.205

3. Bovine alloreactive cytotoxic cells generated in vitro: target specificity in relation to BoLA phenotype.

Authors: A J Teale; W I Morrison; B M Goddeeris; C M Groocock; D A Stagg; R L Spooner
Journal: Immunology Date: 1985-06 Impact factor: 7.397

4. Primary in vitro sensitization of virus specific cytotoxic T lymphocytes.

Authors: H Jung; K Pfizenmaier; A Starzinski-Powitz; M Röllinghoff; H Wagner
Journal: Immunology Date: 1978-04 Impact factor: 7.397

5. Antigen-specific helper T cells recognize determinants encoded in the H-2D region of the H-2 gene complex.

Authors: L M Pilarski; T G Wegmann
Journal: Immunogenetics Date: 1984 Impact factor: 2.846

6. Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.

Authors: S L Swain
Journal: Proc Natl Acad Sci U S A Date: 1981-11 Impact factor: 11.205

7. Receptor specificity, functional characteristics, and cell-surface phenotype of a highly selected anti-I-Ab-specific, long-term T-cell line.

Authors: B E Elliott; A Kimura; A B Peck; Z A Nagy; H Wigzell
Journal: Immunogenetics Date: 1981-03-01 Impact factor: 2.846