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Literature DB >> 5323606

Localization of a basic protein in the myelin of various species with the aid of fluorescence and electron microscopy.

Abstract

In this study, alanine was shown to be the N-terminal amino acid of a basic protein of low molecular weight that was isolated from either human or guinea pig brain. Antibodies prepared against the guinea pig protein were labeled with either fluorescein or ferritin. Studies with the labeled antibodies showed that an immunohistochemically similar protein is found in the myelin sheaths of central and peripheral nervous tissues of chicken and frog and a variety of mammalian species. Loss of integrity of the myelin during processing was shown to enhance markedly the antigen-antibody reaction.

Entities: Chemical Disease Species

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Year: 1965 PMID： 5323606 PMCID： PMC2106706 DOI： 10.1083/jcb.26.1.157

Source DB: PubMed Journal: J Cell Biol ISSN： 0021-9525 Impact factor: 10.539

13 in total

1. IMMUNOCHEMICAL STAINING FOR ELECTRON MICROSCOPY.

Authors: R A RIFKIND; K C HSU; C MORGAN
Journal: J Histochem Cytochem Date: 1964-02 Impact factor: 2.479

2. REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES.

Authors: J H FRENSTER; V G ALLFREY; A E MIRSKY
Journal: Proc Natl Acad Sci U S A Date: 1963-12 Impact factor: 11.205

3. Physical characteristics of proteins of the electron transfer system and interpretation of the structure of the mitochondrion.

Authors: R S CRIDDLE; R M BOCK; D E GREEN; H TISDALE
Journal: Biochemistry Date: 1962-09 Impact factor: 3.162

Localization of a basic protein in the myelin of various species with the aid of fluorescence and electron microscopy.

1. IMMUNOCHEMICAL STAINING FOR ELECTRON MICROSCOPY.

2. REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES.

3. Physical characteristics of proteins of the electron transfer system and interpretation of the structure of the mitochondrion.

4. The amino acid composition of proteins isolated from the ribonucleoprotein particles of rat liver.

5. The presence of basic proteins in microsomes.

6. Isothiocyanate compounds as fluorescent labeling agents for immune serum.

7. A study of the proteinase content and the chromatography of thymus histones.

8. Recent developments in techniques for terminal and sequence studies in peptides and proteins.

9. Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults.

10. Chromatographic fractionation of calf thymus histone.

1. Expression and localization of myosin-1d in the developing nervous system.

Review 2. Proteins of myelin and their metabolism.

3. Complex-formation between triphosphoinositide and experimental allergic encephalitogenic protein.

4. Experimental allergic encephalomyelitis. Isolation of basic proteins and polypeptides from central nervous tissue.

5. Immunocytochemical localization of basic protein in major dense line regions of central and peripheral myelin.

6. Immunocytochemical localization studies of myelin basic protein.

7. Cuprizone demyelination induces a unique inflammatory response in the subventricular zone.

8. [Identification and cytochemical study of an extranuclear basic protein in the spermatozoa of decapod crustaceans].