The effect of methandrostenolone on nitrogen excretion following open-heart surgery.

An attempt was made to assess the effect of an anabolic hormone in the postoperative phase. Methandrostenolone (Danabol) was given to groups of adults and children undergoing open-heart surgery, and the results were compared with those obtained in control groups. No difference in the clinical picture could be found between the treated and the untreated groups, or in the total amount of nitrogen excreted during six days following the operation. In both treated groups the urinary volume was increased, resulting in a decreased urinary nitrogen concentration.