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Literature DB >> 5317080

The effect of metrifonate on Brugia pahangi infections in domestic cats.

D A Denham, T Ponnudurai, G S Nelson, F Guy, R Rogers.

Abstract

Metrifonate, an organophosphorus compound, caused a decline in the number of microfilariae in domestic cats experimentally infected with Brugia pahangi. It was found that the drug was active against both microfilariae and macrofilariae, but probably its greatest effect was on the macrofilarial stages. It is suggested that the drug should be used in filarial infections of man on a trial basis.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1971 PMID： 5317080 PMCID： PMC2427939

Source DB: PubMed Journal: Bull World Health Organ ISSN： 0042-9686 Impact factor: 9.408

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References

13 in total

1. STUDIES ON EPIDEMIOLOGY AND CONTROL OF FILARIASIS: OBSERVATIONS ON THE CARRIERS OF WUCHERERIA BANCROFTI IN THE AMAMI ISLANDS WITH SPECIAL REFERENCE TO THE EFFECTS AND SIDE-REACTIONS OF DIETHYLCARBAMAZINE.

Authors: M SASA; T OSHIMA; K SATO; G MITSUI; F SUGATA; S NISHI; H YAMAMOTO; I TADA; E MOTOI
Journal: Jpn J Exp Med Date: 1963-08

2. Developmental stages of Brugia pahangi in the final host.

Authors: J F SCHACHER
Journal: J Parasitol Date: 1962-10 Impact factor: 1.276

3. Experimental transmission of Brugia malayi and B. pahangi to man.

Authors: J F EDESON; T WILSON; R H WHARTON; A B LAING
Journal: Trans R Soc Trop Med Hyg Date: 1960-05 Impact factor: 2.184

4. Studies on filariasis in Malaya: the effect of diethylcarbamazine on Brugia malayi and B. pahangi in domestic cats.

Authors: J F EDESON; A B LAING
Journal: Ann Trop Med Parasitol Date: 1959-12

5. On the adult morphology of Wuchereria sp. (malayi?) from a monkey (Macaca irus) and from cats in Malaya, and on Wuchereria pahangi n.sp. from a dog and a cat.

Authors: J J BUCKLEY; J F EDESON
Journal: J Helminthol Date: 1956 Impact factor: 2.170

10. Studies on filariasis in Malaya: treatment of Wuchereria malayi-carriers with monthly or weekly doses of diethylcarbamazine (banocide).

Authors: J F EDESON; R H WHARTON
Journal: Ann Trop Med Parasitol Date: 1958-03

The effect of metrifonate on Brugia pahangi infections in domestic cats.

1. STUDIES ON EPIDEMIOLOGY AND CONTROL OF FILARIASIS: OBSERVATIONS ON THE CARRIERS OF WUCHERERIA BANCROFTI IN THE AMAMI ISLANDS WITH SPECIAL REFERENCE TO THE EFFECTS AND SIDE-REACTIONS OF DIETHYLCARBAMAZINE.

2. Developmental stages of Brugia pahangi in the final host.

3. Experimental transmission of Brugia malayi and B. pahangi to man.

4. Studies on filariasis in Malaya: the effect of diethylcarbamazine on Brugia malayi and B. pahangi in domestic cats.

5. On the adult morphology of Wuchereria sp. (malayi?) from a monkey (Macaca irus) and from cats in Malaya, and on Wuchereria pahangi n.sp. from a dog and a cat.

6. Hetrazan in the treatment of filariasis due to Wuchereria malayi.

7. Comparison of a counting chamber and thick smear methods of counting microfilariae.

8. Enhancement of the density of circulating microfilariae with diethylcarbamazine.

9. Ostertagia circumcincta: methyridine and tetramisole against third stage larvae.

10. Studies on filariasis in Malaya: treatment of Wuchereria malayi-carriers with monthly or weekly doses of diethylcarbamazine (banocide).