Literature DB >> 5315912

Aspirin and alcohol in gastrointestinal haemorrhage.

C D Needham, J Kyle, P F Jones, S J Johnston, D F Kerridge.   

Abstract

The intake of aspirin, of alcohol, and of a combination of both, among 817 patients admitted for gastrointestinal haemorrhage is reported. The incidence of ingestion in six diagnostic groups is compared with that in two control groups. Analysis confirms that there is a markedly significant association between overt haemorrhage and the ingestion of aspirin, but this was not shown for alcohol taken alone: the combination of aspirin and alcohol showed a highly significant synergistic effect.

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Year:  1971        PMID： 5315912      PMCID： PMC1411878          DOI： 10.1136/gut.12.10.819

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  6 in total

1.  Aspirin and gastric haemorrhage.

Authors:  A MUIR; I A COSSAR
Journal:  Lancet       Date:  1959-03-14       Impact factor: 79.321

2.  Gastrointestinal haemorrhage and salicylates.

Authors:  A S ALVAREZ; W H SUMMERSKILL
Journal:  Lancet       Date:  1958-11-01       Impact factor: 79.321

3.  The influence of some of the salicyl compounds (and alcoholic beverages) on the natural history of peptic ulcer.

Authors:  R K BROWN; N MITCHELL
Journal:  Gastroenterology       Date:  1956-08       Impact factor: 22.682

Review 4.  Epidemiological evidence for the association of aspirin and acute gastrointestinal bleeding.

Authors:  M J Langman
Journal:  Gut       Date:  1970-07       Impact factor: 23.059

5.  Relationship between aspirin taking and gastroduodenal haemorrhage.

Authors:  D J Parry; P H Wood
Journal:  Gut       Date:  1967-06       Impact factor: 23.059

6.  Alcohol, aspirin, and gastrointestinal bleeding.

Authors:  K Goulston; A R Cooke
Journal:  Br Med J       Date:  1968-12-14
  6 in total
  16 in total

Review 1.  The biochemical pathology of aspirin-induced gastric damage.

Authors:  K D Rainsford
Journal:  Agents Actions       Date:  1975-10

Review 2.  The role of the mucosal barrier in drug-induced gastric ulceration and erosions.

Authors:  A R Cooke
Journal:  Am J Dig Dis       Date:  1976-02

Review 3.  Pharmacokinetic drug interactions with nonsteroidal anti-inflammatory drugs.

Authors:  R K Verbeeck
Journal:  Clin Pharmacokinet       Date:  1990-07       Impact factor: 6.447

4.  A review of papers purporting to show a cause-and-effect relationship between aspirin ingestion and massive gastrointestinal haemorrhage.

Authors:  E Shirley
Journal:  Proc R Soc Med       Date:  1977

5.  Gastric protection by misoprostol against 1300 mg of aspirin. An endoscopic study.

Authors:  F E Silverstein; M B Kimmey; D R Saunders; D S Levine
Journal:  Dig Dis Sci       Date:  1986-02       Impact factor: 3.199

Review 6.  The role of acid in the pathogenesis of aspirin-induced gastrointestinal erosions and hemorrhage.

Authors:  A R Cooke
Journal:  Am J Dig Dis       Date:  1973-03

7.  Editorial: Aspirin and what else?

Authors: 
Journal:  Br Med J       Date:  1974-07-06

8.  Abnormal aspirin metabolism in patients with cirrhosis and its possible relationship to bleeding in cirrhotics.

Authors:  R Menguy; L Desbaillets; S Okabe; Y F Masters
Journal:  Ann Surg       Date:  1972-09       Impact factor: 12.969

9.  Acute upper-gastrointestinal hemorrhage. New observations on an old problem.

Authors:  D Y Graham; R E Davis
Journal:  Am J Dig Dis       Date:  1978-01

10.  Aspirin, paracetamol, and haematemesis and melaena.

Authors:  D Coggon; M J Langman; D Spiegelhalter
Journal:  Gut       Date:  1982-04       Impact factor: 23.059
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