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Literature DB >> 5313000

Immunization against neonatal tetanus in New Guinea. 4. Comparison of tetanus antitoxin titres obtained by haemagglutination and toxin neutralization in mice.

M C Hardegree, M F Barile, M Pittman, C J Maloney, F Schofield, R Maclennan.

Abstract

Haemagglutination (HA) has been used frequently for the titration of tetanus antitoxin but published results have varied in relation to the "unitage" determined by the mouse toxin-neutralization test (TN). This report gives the results of the titration of a group of sera by haemagglutination and compares them with the results obtained by toxin neutralization. Although there was marked variation between HA and TN titres of individual sera, results indicated that haemagglutination is a useful procedure for the over-all evaluation of the antitoxin responses to tetanus toxoids in field studies.

Entities: Disease Species

Mesh：

Substances：
Antibodies

Year: 1970 PMID： 5313000 PMCID： PMC2427686

Source DB: PubMed Journal: Bull World Health Organ ISSN： 0042-9686 Impact factor: 9.408

23 in total

1. Tetanus antitoxin titration by haemagglutination.

Authors: A J FULTHORPE
Journal: J Hyg (Lond) Date: 1957-09

2. Studies of tetanus toxin and antitoxin in human sera. II. Comparison of hemagglutination and mouse neutralization tests for determining circulating human tetanus antitoxin.

Authors: J D MARSHALL; N SCHNEIDER; F J SMITH
Journal: Med Techn Bull Date: 1957 Jul-Aug

3. Tetanus antitoxin tittration by haemagglutination at a low level of test.

Authors: A J FULTHORPE
Journal: J Hyg (Lond) Date: 1958-06

4. Micromethods for the study of proteins and antibodies. II. Specific applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells.

Authors: A B STAVITSKY
Journal: J Immunol Date: 1954-05 Impact factor: 5.422

5. Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells.

Authors: A B STAVITSKY
Journal: J Immunol Date: 1954-05 Impact factor: 5.422

6. Tetanus immune globulin from selected human plasmas. Six years of experience with a screening method.

Authors: L Levine; L Wyman; J A McComb
Journal: JAMA Date: 1967-04-24 Impact factor: 56.272

7. Passive hemagglutination procedures for protein and polysaccharide antigens using erythrocytes stabilized by aldehydes.

Authors: A A Hirata; M W Brandriss
Journal: J Immunol Date: 1968-03 Impact factor: 5.422

8. Immunization against neonatal tetanus in New Guinea. 3. The toxin-neutralization test and the response of guinea-pigs to the toxoids as used in the immunization schedules in New Guinea.

Authors: M F Barile; M C Hardegree; M Pittman
Journal: Bull World Health Organ Date: 1970 Impact factor: 9.408

9. Immunization against neonatal tetanus in New Guinea. Antitoxin response of pregnant women to adjuvant and plain toxoids.

Authors: R MacLennan; F D Schofield; M Pittman; M C Hardegree; M F Barile
Journal: Bull World Health Organ Date: 1965 Impact factor: 9.408

10. The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera.

Authors: S V BOYDEN
Journal: J Exp Med Date: 1951-02 Impact factor: 14.307

7 in total

1. DTP immunization status and tetanus antitoxin titers of Mexican American children ages six months through eleven years.

Authors: P J Gergen; T Ezzati; H Russell
Journal: Am J Public Health Date: 1988-11 Impact factor: 9.308

2. Immunologic and genetic factors influencing reproduction. A review.

Authors: T J Gill; C F Repetti
Journal: Am J Pathol Date: 1979-05 Impact factor: 4.307

3. A radioimmunoassay for tetanus antibodies using protein A - containing Staphylococcus aureus.

Authors: E Habermann; E Horváth; W Schaeg
Journal: Med Microbiol Immunol Date: 1977-12-27 Impact factor: 3.402

4. Comparison of passive hemagglutination with Turkey erythrocyte assay, enzyme-linked immunosorbent assay, and counterimmunoelectrophoresis assay for serological evaluation of tetanus immunity.

Authors: L Pitzurra; F Bistoni; M Pitzurra; L Bastianini; S Perito; A Vecchiarelli; P Marconi
Journal: J Clin Microbiol Date: 1983-03 Impact factor: 5.948