Self-injected retinal emboli.

Twelve patients with bilateral intraretinal talc emboli were examined. Each patient had self-injected large doses of methylphenidate (Ritalin) for one or more years. All fundi showed yellow-white particles in the macular area, and two eyes had reduced vision secondary to retinal vascular occlusion. The clinical syndrome, ophthalmoscopic appearance, and fluorescein angiographic findings of self-injected retinal emboli are presented, and the pathogenesis is discussed.