Literature DB >> 530578

Early detection of retinal involvement in diabetes by vitreous fluorophotometry.

J G Cunha-Vaz, M F Goldberg, C Vygantas, J Noth.   

Abstract

Vitreous fluorophotometry is a new quantitative method for evaluation of the blood-retinal barrier (BRB). The application of this method to a series of diabetic patients with apparently normal fundi revealed the presence of a significant breakdown of the BRB in the early stages of retinal involvement in diabetes. This alteration of the BRB appears to be the earliest clinically detectable change to occur in the retina in diabetes. Higher vitreous fluorophotometry values, indicating a more marked breakdown of the BRB, occurred in patients who were under worse metabolic control. Higher vitreous fluorophotometry values were also associated with the development of visible retinal lesions.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 530578     DOI： 10.1016/s0161-6420(79)35516-6

Source DB:  PubMed          Journal:  Ophthalmology        ISSN： 0161-6420            Impact factor:   12.079


  10 in total

Review 1.  Molecular imaging of retinal disease.

Authors:  Megan E Capozzi; Andrew Y Gordon; John S Penn; Ashwath Jayagopal
Journal:  J Ocul Pharmacol Ther       Date:  2013-02-19       Impact factor: 2.671

2.  Optimized protocol for Fluorotron Master.

Authors:  J R Gray; M A Mosier; B M Ishimoto
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1985       Impact factor: 3.117

3.  An evaluation of the clinical role of vitreous fluorophotometry.

Authors:  P C McCullough; C J Koester; C J Campbell; E A Anderson
Journal:  Trans Am Ophthalmol Soc       Date:  1983

4.  Retinal microangiopathy and pigment epithelial lesions in subjects with normal, borderline, and decreased oral glucose tolerance.

Authors:  P Algvere; S Efendić; R Luft; A Wajngot
Journal:  Br J Ophthalmol       Date:  1985-06       Impact factor: 4.638

5.  Clinical applications of fluorometry.

Authors:  L J Blanksma; A C Kooijman; J H Roze; J V Siertsema
Journal:  Doc Ophthalmol       Date:  1983-02-28       Impact factor: 2.379

6.  Alteration of choroidal circulation in the foveal region in patients with type 2 diabetes.

Authors:  T Nagaoka; N Kitaya; R Sugawara; H Yokota; F Mori; T Hikichi; N Fujio; A Yoshida
Journal:  Br J Ophthalmol       Date:  2004-08       Impact factor: 4.638

7.  Outward transport of fluorescein from the vitreous in aphakic eyes.

Authors:  K Miyake; T Miyake; C Miyake; M Asakura; K Maekubo
Journal:  Br J Ophthalmol       Date:  1985-06       Impact factor: 4.638

8.  Effect of morphological abnormalities on blood retinal barrier permeability in diabetic retinopathy.

Authors:  J M van Gerven; J P Boot; H H Lemkes; J A van Best
Journal:  Doc Ophthalmol       Date:  1992       Impact factor: 2.379

9.  Vitreous fluorophotometry in optic nerve disease.

Authors:  L S Braude; J G Cunha-Vaz; M Frenkel
Journal:  Br J Ophthalmol       Date:  1982-09       Impact factor: 4.638

10.  Alterations in the Choroidal Sublayers in Relationship to Severity and Progression of Diabetic Retinopathy: A Swept-Source OCT Study.

Authors:  Erica W T Kung; Victor T T Chan; Ziqi Tang; Dawei Yang; Zihan Sun; Yu Meng Wang; C H Chan; Michael C H Kwan; Jian Shi; Carol Y Cheung
Journal:  Ophthalmol Sci       Date:  2022-02-25
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.