| Literature DB >> 529029 |
Abstract
The examples are given to show how Metzler's nonlinear regression program can be used to estimate parameters in a model with multiple dosing. The model of one example is a set of equations involving sums of exponentials, whereas the other model is a set of differential equations reflecting first order absorption and Michaelis-Menten excretion. In both cases no data were given in one of the dosing intervals.Mesh：
Substances：
Year: 1979 PMID： 529029 DOI： 10.1007/BF01061214
Source DB: PubMed Journal: J Pharmacokinet Biopharm ISSN： 0090-466X