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Literature DB >> 5289716

Trials of intranasally administered rubella vaccine.

Abstract

No evidence of vaccine virus transmission was found in two studies where Wistar RA 27/3 rubella vaccine was administered intranasally. Vaccine was immunogenic in all of 23 vaccinated children in one study, while in the other only 5 of the 11 vaccinees developed antibody. The reduced seroconversion rate in the latter study appears to have been caused by one or a combination of factors, including the vaccination technique, the presence of infective nasal conditions in vaccinees and the titre of vaccine used.

Entities: Disease Species

Mesh：

Substances：

Year: 1971 PMID： 5289716 PMCID： PMC2131036 DOI： 10.1017/s0022172400021811

Source DB: PubMed Journal: J Hyg (Lond) ISSN： 0022-1724

11 in total

Review 1. Some recent trends in vaccination against respiratory viruses.

Authors: D A Tyrrell
Journal: Br Med Bull Date: 1969-05 Impact factor: 4.291

2. The effect of kaolin on immunoglobulins: an improved technique to remove the nonspecific serum inhibitor of reovirus hemagglutination.

Authors: J J Mann; R D Rossen; J R Lehrich; J A Kasel
Journal: J Immunol Date: 1967-06 Impact factor: 5.422

Trials of intranasally administered rubella vaccine.

Review 1. Some recent trends in vaccination against respiratory viruses.

2. The effect of kaolin on immunoglobulins: an improved technique to remove the nonspecific serum inhibitor of reovirus hemagglutination.

3. Immunisation of schoolchildren with rubella (RA27-3) vaccine. Intranasal and subcutaneous administration.

4. A simple method for removal of rubella hemagglutination inhibitors from serum adaptable to finger-tip blood.

5. Clinical and serologic studies of an outbreak of rubella in a vaccinated population.

6. Rubella: reinfection of vaccinated and naturally immune persons exposed in an epidemic.

7. Rubella vaccine trial in children.

8. Attenuation of RA 27-3 rubella virus in WI-38 human diploid cells.

9. [The use of pigeon eruthrocytes in the hemagglutination inhibition test for rubella].

10. Rubella-virus hemagglutination-inhibition test.

1. WRL 105 strain live attenuated influenza vaccine; comparison of one and two dose schedules.

Review 2. Rubella vaccines: past, present and future.

3. The administration of drugs and vaccines by the intranasal route.

4. Rubella vaccination.