Literature DB >> 5289028

Evaluation of the effects of chemical mutagens on man: the long road ahead.

J V Neel.   

Abstract

By analogy with the problem of evaluating the genetic risks of radiation, it appears that it will be extremely difficult to assess the mutagenicity for man of the wide range of chemicals to which human populations are currently exposed. Nevertheless, the potential significance of this problem calls for a major effort at such an evaluation.

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Year:  1970        PMID： 5289028      PMCID： PMC283291          DOI： 10.1073/pnas.67.2.908

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  29 in total

1.  Radiation dose rate and mutation frequency.

Authors:  W L RUSSELL; L B RUSSELL; E M KELLY
Journal:  Science       Date:  1958-12-19       Impact factor: 47.728

2.  [Mutagenic drugs].

Authors:  A BARTHELMESS
Journal:  Arzneimittelforschung       Date:  1956-04

3.  A cohort-type study of survival in the children of parents exposed to atomic bombings.

Authors:  H Kato; W J Schull; J V Neel
Journal:  Am J Hum Genet       Date:  1966-07       Impact factor: 11.025

4.  The genetic load of a human population due to cytostatic agents.

Authors:  F Vogel; P Jäger
Journal:  Humangenetik       Date:  1969

5.  Genetic effects of spermatogonial irradiation on growth and age at sexual maturity in rats.

Authors:  B A Taylor; A B Chapman
Journal:  Genetics       Date:  1969-10       Impact factor: 4.562

6.  Chemical mutagens in the human environment.

Authors:  S S Epstein; H Shafner
Journal:  Nature       Date:  1968-07-27       Impact factor: 49.962

7.  Mutagenicity tests in mice. I. The dominant lethal method and the control problem.

Authors:  G Röhrborn
Journal:  Humangenetik       Date:  1968

8.  Induction of paternal sex-chromosome losses and deletions and of autosomal gene mutations by the treatment of mouse post-meiotic germ cells with triethylenemelamine.

Authors:  B M Cattanach
Journal:  Mutat Res       Date:  1967-02       Impact factor: 2.433

9.  Some further observations on the sex ratio among infants born to survivors of the atomic bombings of Hiroshima and Nagasaki.

Authors:  W J Schull; J V Neel; A Hashizume
Journal:  Am J Hum Genet       Date:  1966-07       Impact factor: 11.025

10.  The number of balanced polymorphisms that can be maintained in a natural population.

Authors:  J A Sved; T E Reed; W F Bodmer
Journal:  Genetics       Date:  1967-03       Impact factor: 4.562
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  3 in total

Review 1.  Analytic review: some current problems of human population genetics.

Authors:  L L Cavalli-Sforza
Journal:  Am J Hum Genet       Date:  1973-01       Impact factor: 11.025

2.  Protein mapping by combined isoelectric focusing and electrophoresis of mouse tissues. A novel approach to testing for induced point mutations in mammals.

Authors:  J Klose
Journal:  Humangenetik       Date:  1975

3.  The protein-mapping-method employed to test for chemically induced point mutations in mice.

Authors:  J Klose
Journal:  Arch Toxicol       Date:  1977-09-21       Impact factor: 5.153
  3 in total

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