| Literature DB >> 5289023 |
M K Jain, R H Marks, E H Cordes.
Abstract
A kinetic model describing conduction changes across excitable membranes is proposed. It assumes that a population of discrete membrane sites is distributed among several distinct functional states determined by the voltage across the membrane. Interconversion of these states is postulated to occur by first-order reactions. It provides a satisfactory description of the central aspects of excitable membrane behavior, including current-time and current-voltage relationships, action potential, and effects of inhibitors.Mesh：
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Year: 1970 PMID： 5289023 PMCID： PMC283276 DOI： 10.1073/pnas.67.2.799
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205