Literature DB >> 5288766

Translocation of messenger RNA and "accommodation" of fMet-tRNA.

S S Thach, R E Thach.   

Abstract

Messenger RNA is moved a distance of approximately three nucleotides in the 5' direction relative to the ribosome during the translocation of peptidyl-tRNA from the A to the P site. This movement is catalyzed by G factor and is dependent on the hydrolysis of GTP. In contrast, mRNA is not moved during the f(2)-catalyzed hydrolysis of GTP that is involved in the activation of ribosome-bound fMet-tRNA. This second type of GTP-dependent reaction has been named "Accommodation".

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 5288766      PMCID： PMC389294          DOI： 10.1073/pnas.68.8.1791

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  32 in total

Review 1.  THE SYNTHESIS OF PROTEINS UPON RIBOSOMES.

Authors:  J D WATSON
Journal:  Bull Soc Chim Biol (Paris)       Date:  1964

2.  Role of guanosine 5'-triphosphate in the initiation of Peptide synthesis, I. Synthesis of formylmethionyl-puromycin.

Authors:  J W Hershey; R E Thach
Journal:  Proc Natl Acad Sci U S A       Date:  1967-03       Impact factor: 11.205

3.  The interrelationship between guanosine triphosphatase and amino acid polymerization.

Authors:  Y Nishizuka; F Lipmann
Journal:  Arch Biochem Biophys       Date:  1966-09-26       Impact factor: 4.013

4.  Stability of different ribosomal complexes with initiator transfer RNA and synthetic messenger RNA.

Authors:  M Grunberg-Manago; B F Clark; M Revel; P S Rudland; J Dondon
Journal:  J Mol Biol       Date:  1969-02-28       Impact factor: 5.469

5.  The role of an aminoacyl-tRNA-GTP-protein complex in polypeptide synthesis.

Authors:  J M Ravel; R L Shorey; C W Garner; R C Dawkins; W Shive
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1969

6.  Binding of guanosine 5'-triphosphate by soluble factors required for polypeptide synthesis.

Authors:  R Ertel; N Brot; B Redfield; J E Allende; H Weissbach
Journal:  Proc Natl Acad Sci U S A       Date:  1968-03       Impact factor: 11.205

7.  Role of the formylmethionine codon AUG in phasing translation of synthetic messenger RNA.

Authors:  T A Sundararajan; R E Thach
Journal:  J Mol Biol       Date:  1966-08       Impact factor: 5.469

8.  Role of guanosine 5'-triphosphate in the initiation of peptide synthesis, II. Synthesis of dipeptides.

Authors:  R E Thach; K F Dewey; N Mykolajewycz
Journal:  Proc Natl Acad Sci U S A       Date:  1967-04       Impact factor: 11.205

9.  Polypeptide chain initiation in E. coli: studies on the function of initiation factor F1.

Authors:  Y B Chae; R Mazumder; S Ochoa
Journal:  Proc Natl Acad Sci U S A       Date:  1969-07       Impact factor: 11.205

10.  Breakdown by streptomycin of initiation complexes formed on ribosomes of Escherichia coli.

Authors:  J Modolell; B D Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205
View more
  11 in total

1.  Use of single-stranded DNA oligonucleotides in programming ribosomes for translation.

Authors:  R D Ricker; A Kaji
Journal:  Nucleic Acids Res       Date:  1991-12-11       Impact factor: 16.971

2.  Aminoacyl-tRNA binding at the recognition site is the first step of the elongation cycle of protein synthesis.

Authors:  J A Lake
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

3.  A novel conformational change of the anticodon region of tRNAPhe (yeast).

Authors:  C Urbanke; G Maass
Journal:  Nucleic Acids Res       Date:  1978-05       Impact factor: 16.971

Review 4.  Translation of the genome of a ribonucleic acid bacteriophage.

Authors:  M Kozak; D Nathans
Journal:  Bacteriol Rev       Date:  1972-03

5.  Elongation factors EF Tu and EF G interact at related sites on ribosomes.

Authors:  D L Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205

6.  Functional heterogeneity of the 30S ribosomal subunit of Escherichia coli. II. Effect of S21 on initiation.

Authors:  J van Duin; P H van Knippenberg; M Dieben
Journal:  Mol Gen Genet       Date:  1972

7.  Initiator tRNA may recognize more than the initiation codon in mRNA: a model for translational initiation.

Authors:  M C Ganoza; P Marliere; E C Kofoid; B G Louis
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205

8.  Monoribosomal attachment to messenger ribonucleic acid in sodium fluoride-treated rabbit reticulocytes.

Authors:  M Geraghty; M Galler; F Schiffman; M Freedman
Journal:  Biochem J       Date:  1973-06       Impact factor: 3.857

9.  Structural and functional properties of ribosomes crosslinked with dimethylsuberimidate.

Authors:  L I Slobin
Journal:  Proc Natl Acad Sci U S A       Date:  1972-12       Impact factor: 11.205

10.  Three widely separated positions in the 16S RNA lie in or close to the ribosomal decoding region; a site-directed cross-linking study with mRNA analogues.

Authors:  O Dontsova; S Dokudovskaya; A Kopylov; A Bogdanov; J Rinke-Appel; N Jünke; R Brimacombe
Journal:  EMBO J       Date:  1992-08       Impact factor: 11.598
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.