Literature DB >> 528564

Comparison of a water-soluble and a water-insoluble podophyllotoxin derivative in murine neoplasms.

W Kreis, A Soricelli.   

Abstract

Comparison of a water-soluble (27-487) with a water-insoluble (VP-16-213) podophyllotoxin derivative in seven murine neoplasms revealed slight therapeutic superiortiy of VP-16-213 but also slightly greater toxicity when compared with 27-487. A strikingly good response of the Taper liver tumor to both compounds was observed, providing further incentive to the use of podophyllotoxin derivatives in human hepatomas.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 528564     DOI： 10.1007/BF00410644

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  8 in total

1.  [Therapeutic results using VP 16-213 alone or in combination with 5-fluorouracil in liver cancer (hepatoma)].

Authors:  F Cavalli; L Tschopp; A Gerber; R W Sonntag; H J Ryssel; K W Brunner
Journal:  Schweiz Med Wochenschr       Date:  1977-12-31

2.  Delayed toxicity of epipodophyllotoxin derivatives (VM 26 and VP 16-213), due to a local effect.

Authors:  H Stähelin
Journal:  Eur J Cancer       Date:  1976-11       Impact factor: 9.162

3.  VM26-induced changes in hepatic intermediary metabolism of mice.

Authors:  M Hacker; D Roberts
Journal:  Cancer Res       Date:  1977-09       Impact factor: 12.701

Review 4.  VM 26 and VP 16-213: a comparative analysis.

Authors:  M Rozencweig; D D Von Hoff; J E Henney; F M Muggia
Journal:  Cancer       Date:  1977-07       Impact factor: 6.860

5.  Activity of a new glycosidic lignan derivative (VP 16-213) related to podophyllotoxin in experimental tumors.

Authors:  H Stähelin
Journal:  Eur J Cancer       Date:  1973-03       Impact factor: 9.162

6.  Synthesis and antimitotic activity of glycosidic lignan derivatives related to podophyllotoxin.

Authors:  C Keller-Juslén; M Kuhn; H Stähelin; A von Wartburg
Journal:  J Med Chem       Date:  1971-10       Impact factor: 7.446

7.  Hepatocellular carcinoma in the Malaysian Orang Asli.

Authors:  E Sumithran; K Prathap
Journal:  Cancer       Date:  1976-05       Impact factor: 6.860

8.  A phase II study of adriamycin (NSC 123127) in patients with hepatocellular carcinoma from Zambia and the United States.

Authors:  C L Vogel; A C Bayley; R J Brooker; P P Anthony; J L Ziegler
Journal:  Cancer       Date:  1977-05       Impact factor: 6.860
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.