Literature DB >> 5282924

Comparative trial of three heterologous anti-tetanus sera.

I S Sinclair, J S McCormick, J G Clark.   

Abstract

The three heterologous anti-sera currently provided for tetanus prophylaxis have been compared with reference to the production of untoward reactions in 498 patients, and to the blood antitoxin concentrations produced in 76 patients. Equine serum, although giving rise to more reactions, was the only effective agent in terms of the levels and duration of serum antitoxin concentration produced. The local response to a test dose of any of the three sera is not a reliable guide to immediate or late general reactions.

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Year:  1971        PMID： 5282924      PMCID： PMC2130880          DOI： 10.1017/s0022172400021434

Source DB:  PubMed          Journal:  J Hyg (Lond)        ISSN： 0022-1724


  10 in total

1.  PENICILLIN IN PREVENTION OF TETANUS.

Authors:  J W SMITH
Journal:  Br Med J       Date:  1964-11-21

2.  TETANUS PROPHYLAXIS.

Authors:  C A COX; J KNOWELDEN; W J SHARRARD
Journal:  Br Med J       Date:  1963-11-30

3.  THE PROPHYLACTIC DOSE OF HOMOLOGOUS TETANUS ANTITOXIN.

Authors:  J A MCCOMB
Journal:  N Engl J Med       Date:  1964-01-23       Impact factor: 91.245

4.  The delayed anamnestic response to tetanus toxoid.

Authors:  R D KING; G C KAISER; R E LEMPKE; M H RUSTER
Journal:  Surg Gynecol Obstet       Date:  1963-06

5.  An analysis of tetanus prophylaxis in 3,455 cases.

Authors:  P M BINNS
Journal:  Br J Prev Soc Med       Date:  1961-10

6.  Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen.

Authors:  D W DRESSER
Journal:  Immunology       Date:  1962-05       Impact factor: 7.397

7.  Unreliability of local reactions to serum as tests for general sensitivity.

Authors:  L J LAURENT; H J PARISH
Journal:  Br J Prev Soc Med       Date:  1962-04

8.  Role of the thymus in tolerance. V. Suppressive effect of treatment with nonaggregated and aggregated bovine gamma-globulin on specific immune responses in normal adult rats.

Authors:  I Gery; B H Waksman
Journal:  J Immunol       Date:  1967-03       Impact factor: 5.422

9.  New approaches to tetanus prophylaxis.

Authors:  S D Rubbo
Journal:  Lancet       Date:  1966-08-27       Impact factor: 79.321

10.  Duration of immunity after active immunisation against tetanus.

Authors:  W G White; G M Barnes; A H Griffith; D Gall; E Barker; J W Smith
Journal:  Lancet       Date:  1969-07-12       Impact factor: 79.321
  10 in total

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