Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 High incidence of the silent allele at cholinesterase locus I in Vysyas of Andhra Pradesh (S. India).

Literature DB >> 527975

High incidence of the silent allele at cholinesterase locus I in Vysyas of Andhra Pradesh (S. India).

Abstract

Four-hundred and ninety individuals belonging to the Vysya caste from Andhra Pradesh were screened for pseudocholinesterase variants at the E1 and E2 locus. A high incidence of the silent allele (gene frequency=0.1112) was recorded with homozygotes exceeding 2% of the population. Dibucaine- and fluoride-resistant alleles were found in a heterozygous form with the usual alleles in four individuals each. No C5+ variant at the E2 locus was found.

Entities: Chemical Gene

Mesh：

Substances：

Year: 1979 PMID： 527975 DOI： 10.1007/BF00284608

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

12 in total

1. COMPLETE PSEUDOCHOLINESTERASE DEFICIENCY: GENETIC AND IMMUNOLOGIC CHARACTERIZATION.

Authors: W HODGKIN; E R GIBLETT; H LEVINE; W BAUER; A G MOTULSKY
Journal: J Clin Invest Date: 1965-03 Impact factor: 14.808

2. Differential inhibition of human serum cholinesterase with fluoride: recognition of two new phenotypes.

Authors: H HARRIS; M WHITTAKER
Journal: Nature Date: 1961-07-29 Impact factor: 49.962

3. Inheritance of two types of deficiency of human serum cholinesterase.

Authors: E M Scott
Journal: Ann Hum Genet Date: 1973-10 Impact factor: 1.670

4. Genetic survey in the population of Assam. II. Serum protein and erythrocyte enzyme polymorphisms.

Authors: H W Goedde; H G Benkmann; S Singh; B M Das; M R Chakravartti; H Delbrück; G Flatz
Journal: Hum Hered Date: 1972 Impact factor: 0.444

5. High frequency of atypical pseudocholinesterase gene among Iraqi and Iranian Jews.

Authors: A Szeinberg; S Pipano; M Assa; J H Medalie; H N Neufeld
Journal: Clin Genet Date: 1972 Impact factor: 4.438

6. A study of the pseudocholinesterase polymorphism among a panjabi population.

Authors: S Singh; M K Amma; K N Sareen; H W Goedde
Journal: Hum Hered Date: 1971 Impact factor: 0.444

7. Discrimination of phenotypes in human serum cholinesterase deficiency.

Authors: E M Scott; D D Weaver; R C Wright
Journal: Am J Hum Genet Date: 1970-07 Impact factor: 11.025

Review 8. On the geographical distribution of pseudocholinesterase variants.

Authors: H Steegmüller
Journal: Humangenetik Date: 1975

9. Heterogeneity in the silent gene phenotype of psudocholinesterase of human serum.

Authors: K Altland; H W Goedde
Journal: Biochem Genet Date: 1970-04 Impact factor: 1.890

10. Hereditary deficiency of pseudocholinesterase in Eskimos.

Authors: B B Gutsche; E M Scott; R C Wright
Journal: Nature Date: 1967-07-15 Impact factor: 49.962

6 in total

Review 1. Complex genetic origin of Indian populations and its implications.

Authors: Rakesh Tamang; Lalji Singh; Kumarasamy Thangaraj
Journal: J Biosci Date: 2012-11 Impact factor: 1.826

2. Identification of a frameshift mutation responsible for the silent phenotype of human serum cholinesterase, Gly 117 (GGT----GGAG).

Authors: C P Nogueira; M C McGuire; C Graeser; C F Bartels; M Arpagaus; A F Van der Spek; H Lightstone; O Lockridge; B N La Du
Journal: Am J Hum Genet Date: 1990-05 Impact factor: 11.025

Review 6. Naturally Occurring Genetic Variants of Human Acetylcholinesterase and Butyrylcholinesterase and Their Potential Impact on the Risk of Toxicity from Cholinesterase Inhibitors.

Authors: Oksana Lockridge; Robert B Norgren; Rudolph C Johnson; Thomas A Blake
Journal: Chem Res Toxicol Date: 2016-08-31 Impact factor: 3.739