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Literature DB >> 5276285

Production of 19S IgM antibodies with restricted heterogeneity from sharks.

Abstract

Two of three nurse sharks, Ginglymostoma cirratum, immunized with streptococcal A-variant vaccine, produced over 7 mg/ml serum of 19S IgM antibody to the group-specific carbohydrate. The light chains of this specific antibody from one shark were separated into multiple bands by disc electrophoresis. The light chains from the other antibody-producing animal were much less heterogeneous and gave only one predominant band.

Entities: Chemical Species

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Year: 1971 PMID： 5276285 PMCID： PMC391180 DOI： 10.1073/pnas.68.1.139

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

9 in total

1. Horse anti-SI immunoglobulins. I. Properties of gamma-M-antibody.

Authors: W C Hill; J J Cebra
Journal: Biochemistry Date: 1965-12 Impact factor: 3.162

2. Phylogeny of immunoglobulin structure and function. II. Immunoglobulins of the nurse shark.

Authors: I W Clem; F De Boutaud; M M Sigel
Journal: J Immunol Date: 1967-12 Impact factor: 5.422

3. Antibodies of restricted heterogeneity for structural study.

Authors: E Haber
Journal: Fed Proc Date: 1970 Jan-Feb

4. Experimental approaches to homogenous antibody populations. Factors controlling the occurrence of antibodies with uniform properties.

Authors: R M Krause
Journal: Fed Proc Date: 1970 Jan-Feb

5. Precipitin activity of rabbit macroglobulin antibody.

Authors: K Lindqvist; D C Bauer
Journal: Immunochemistry Date: 1966-09

6. Studies on the chemical structure of the streptococcal cell wall. I. The identification of a mucopeptide in the cell walls of groups A and A-variant streptococci.

Authors: R M KRAUSE; M MCCARTY
Journal: J Exp Med Date: 1961-07-01 Impact factor: 14.307

7. Phylogeny of immunoglobulin structure and function. I. Immunoglobulins of the lemon shark.

Authors: L W Clem; P A Small
Journal: J Exp Med Date: 1967-05-01 Impact factor: 14.307

8. Phylogeny of immunoglobulin structure and function. V. Valences and association constants of teleost antibodies to a haptenic determinant.

Authors: L W Clem; P A Small
Journal: J Exp Med Date: 1970-09-01 Impact factor: 14.307

9. Characteristics of streptococcal group-specific antibody isolated from hyperimmune rabbits.

Authors: C K Osterland; E J Miller; W W Karakawa; R M Krause
Journal: J Exp Med Date: 1966-04-01 Impact factor: 14.307

9 in total

6 in total

Review 1. Evolution and the molecular basis of somatic hypermutation of antigen receptor genes.

Authors: M Diaz; M F Flajnik; N Klinman
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2001-01-29 Impact factor: 6.237

Review 2. The immunoglobulins of cartilaginous fishes.

Authors: Hanover Matz; Danish Munir; James Logue; Helen Dooley
Journal: Dev Comp Immunol Date: 2020-09-23 Impact factor: 3.636

3. Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: possible role in antigen-driven reactions in the absence of germinal centers.

Authors: M Diaz; A S Greenberg; M F Flajnik
Journal: Proc Natl Acad Sci U S A Date: 1998-11-24 Impact factor: 11.205