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Literature DB >> 5271170

Isolation of temperature-sensitive mutants of L-cells.

L H Thompson, R Mankovitz, R M Baker, J E Till, L Siminovitch, G F Whitmore.

Abstract

Procedures are described for the isolation of conditional lethal mutants of mouse L-60T cells. The mutant lines were temperature sensitive by the following criteria: (a) colony-forming ability, (b) growth in suspension culture, and (c) rate of uptake of tritiated-thymidine.

Entities: Chemical Species

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Year: 1970 PMID： 5271170 PMCID： PMC283055 DOI： 10.1073/pnas.66.2.377

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

13 in total

1. The locus of action of 1-beta-d-arabinofuranosylcytosine in the cell cycle.

Authors: M Karon; S Shirakawa
Journal: Cancer Res Date: 1969-03 Impact factor: 12.701

2. Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents.

Authors: F T Kao; T T Puck
Journal: J Cell Physiol Date: 1969-12 Impact factor: 6.384

3. Mammalian cell genetics. I. Selection and characterization of mutations auxotrophic for L-glutamine or resistant to 8-azaguanine in Chinese hamster cells in vitro.

Authors: E H Chu; P Brimer; K B Jacobson; E V Merriam
Journal: Genetics Date: 1969-06 Impact factor: 4.562

4. Properties and uses of human-mouse hybrid cell lines.

Authors: Y Matsuya; H Green; C Basilico
Journal: Nature Date: 1968-12-21 Impact factor: 49.962

5. Sensitivity of synchronized Chinese hamster cells to ultraviolet light.

Authors: A Han; W K Sinclair
Journal: Biophys J Date: 1969-09 Impact factor: 4.033

6. Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells.

Authors: F T Kao; T T Puck
Journal: Proc Natl Acad Sci U S A Date: 1968-08 Impact factor: 11.205

7. Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro.

Authors: E H Chu; H V Malling
Journal: Proc Natl Acad Sci U S A Date: 1968-12 Impact factor: 11.205

8. Temperature sensitive conditional mutants of monkey kidney cells.

Authors: P M Naha
Journal: Nature Date: 1969-09-27 Impact factor: 49.962

9. Synchronization of mammalian cells with tritiated thymidine.

Authors: G F Whitmore; S Gulyas
Journal: Science Date: 1966-02-11 Impact factor: 47.728

10. Actinomycin D: effects on mouse L-cells.

Authors: S Bacchetti; G F Whitmore
Journal: Biophys J Date: 1969-12 Impact factor: 4.033

20 in total

1. Polyoma and cell DNA synthesis in mouse L cells temperature sensitive for the replication of cell DNA.

Authors:
Journal: J Virol Date: 1976-03 Impact factor: 5.103

2. Isolation of cold-sensitive Chinese hamster cells.

Authors: R A Farber; P Unrau
Journal: Mol Gen Genet Date: 1975-06-19

Review 3. Frontiers in mammalian cell culture.

Authors: W L McKeehan; D Barnes; L Reid; E Stanbridge; H Murakami; G H Sato
Journal: In Vitro Cell Dev Biol Date: 1990-01

4. Growth factor-dependent initiation of DNA replication in nuclei isolated from an interleukin 3-dependent murine myeloid cell line.

Authors: N C Munshi; T G Gabig
Journal: J Clin Invest Date: 1990-01 Impact factor: 14.808

Review 5. Biochemistry of the cell cycle.

Authors: D Lloyd
Journal: Biochem J Date: 1987-03-01 Impact factor: 3.857

6. X-linkage of a human genetic locus that corrects the DNA synthesis lesion in tsC1AGOH mouse cells.

Authors: R E Giles; F H Ruddle
Journal: Genetics Date: 1979-12 Impact factor: 4.562

7. Identification of temperature-sensitive DNA- mutants of Chinese hamster cells affected in cellular and viral DNA synthesis.

Authors: J J Dermody; B E Wojcik; H Du; H L Ozer
Journal: Mol Cell Biol Date: 1986-12 Impact factor: 4.272

8. A mammalian cell mutant with a temperature-sensitive leucyl-transfer RNA synthetase.

Authors: L H Thompson; J L Harkins; C P Stanners
Journal: Proc Natl Acad Sci U S A Date: 1973-11 Impact factor: 11.205

Review 9. Utilization of somatic cell hybrids for genetic studies in man.

Authors: K H Grzeschik
Journal: Humangenetik Date: 1973

10. Deleted chromosome 20 from a patient with Alagille syndrome isolated in a cell hybrid through leucine transport selection: study of three candidate genes.

Authors: J F Deleuze; S Dhorne; J Hazan; E Borghi; N Raynaud; N Pollet; M Meunier-Rotival; J Deschatrette; D Alagille; M Hadchouel
Journal: Mamm Genome Date: 1994-11 Impact factor: 2.957