Literature DB >> 526870

Cardiovascular haemodynamics after induction of anaesthesia with althesin in patients with valvular heart disease.

H Spotoft, J D Korshin, M B Sørensen, P Skovsted.   

Abstract

The haemodynamic effects of the induction of anaesthesia with Althesin 0.1 ml.kg-1 were studied in eight patients with valvular heart disease before tracheal intubation and surgery. A 20 per cent reduction in stroke index was compensated for by an increase in heart rate of similar magnitude. Cardiac index, mean arterial, pulmonary arterial, central venous and pulmonary capillary wedge pressures and systemic vascular resistance were unaffected. Pulmonary vascular resistance declined by nearly 30 per cent. It is therefore conclude that Althesin causes only minimal cardiovascular depression in patients with valvular heart disease.

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Year:  1979        PMID: 526870     DOI: 10.1007/BF03006158

Source DB:  PubMed          Journal:  Can Anaesth Soc J        ISSN: 0008-2856


  15 in total

1.  The effects of althesin on arterial pressure, pulse rate preganglionic sympathetic activity and barostatic reflexes in cats.

Authors:  S Sapthavichaikul; K Wisborg; P Skovsted
Journal:  Can Anaesth Soc J       Date:  1975-09

2.  Histamine release after intravenous application of short-acting hypnotics. A comparison of etomidate, Althesin (CT1341) and propanidid.

Authors:  A Doenicke; W Lorenz; R Beigl; H Bezecny; G Uhlig; L Kalmar; B Praetorius; G Mann
Journal:  Br J Anaesth       Date:  1973-11       Impact factor: 9.166

3.  The pharmacological properties in animals of CT1341--a new steroid anaesthetic agent.

Authors:  K J Child; J P Currie; B Dis; M G Dodds; D R Pearce; D J Twissell
Journal:  Br J Anaesth       Date:  1971-01       Impact factor: 9.166

4.  The immediate cardiovascular effects of Althesin (Glaxo CT 1341), a steroid induction agent, and thiopentone in man.

Authors:  A J Coleman; J W Downing; W P Leary; D G Moyes; M Styles
Journal:  Anaesthesia       Date:  1972-10       Impact factor: 6.955

5.  Cardiovascular effects of althesin in patients with cardiac pathology. Preliminary communication.

Authors:  S G Harrison; B A Sellick
Journal:  Br J Anaesth       Date:  1972-11       Impact factor: 9.166

6.  The effect of Althesin on the heart in situ in the cat.

Authors:  T Gordh
Journal:  Postgrad Med J       Date:  1972-06       Impact factor: 2.401

7.  Pulmonary haemodynamics and myocardial effects of Althesin (CT 1341) in the goat.

Authors:  P Foëx; C Prys-Roberts
Journal:  Postgrad Med J       Date:  1972-06       Impact factor: 2.401

8.  Cardiovascular responses of hypertensive patients to induction of anaesthesia with Althesin.

Authors:  C Prys-Roberts; P Foëx; G P Biro
Journal:  Postgrad Med J       Date:  1972-06       Impact factor: 2.401

9.  Scopolamine on heart rates in man.

Authors:  J S Gravenstein; J I Thornby
Journal:  Clin Pharmacol Ther       Date:  1969 May-Jun       Impact factor: 6.875

10.  Percutaneous catheterization of the internal jugular vein.

Authors:  J Korshin; P V Klauber; V Christensen; P Skovsted
Journal:  Acta Anaesthesiol Scand Suppl       Date:  1978
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