Literature DB >> 526848

Effect of injections of small doses of human fibroblast interferon into genital warts. A pilot study.

G M Scott, G W Csonka.   

Abstract

Eleven male patients with genital warts were given injections of fibroblast interferon (300 u) and placebo into the bases of two similar warts. The changes in size of the treated warts compared with that of the controls suggested that interferon did inhibit the growth of the warts. The dose given was probably insufficient for a dramatic effect. In one patient, however, a wart on the penile shaft was injected with interferon and did disappear within two weeks whereas an untreated meatal wart increased in size.

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Year:  1979        PMID: 526848      PMCID: PMC1045706          DOI: 10.1136/sti.55.6.442

Source DB:  PubMed          Journal:  Br J Vener Dis        ISSN: 0007-134X


  4 in total

1.  On the mechanism of enhancement of human interferon production by actinomycin D and cycloheximide.

Authors:  P B Sehgal; I Tamm; J Vilcek
Journal:  Virology       Date:  1976-03       Impact factor: 3.616

2.  Effect of human fibroblast interferon on vaccination in volunteers.

Authors:  G M Scott; T Cartwright; G LeDu; D Dicker
Journal:  J Biol Stand       Date:  1978-01

3.  Demonstration of virus particles in human genital warts.

Authors:  J D Oriel; J D Almeida
Journal:  Br J Vener Dis       Date:  1970-02

4.  Natural history of genital warts.

Authors:  J D Oriel
Journal:  Br J Vener Dis       Date:  1971-02
  4 in total
  11 in total

1.  Randomised double-blind trial of recombinant interferon-beta for condyloma acuminatum.

Authors:  J Monsonego; G Cessot; S E Ince; A R Galazka; A K Abdul-Ahad
Journal:  Genitourin Med       Date:  1996-04

Review 2.  Interferon: therapeutic fact or fiction for the '80s?

Authors:  G M Scott; D A Tyrrell
Journal:  Br Med J       Date:  1980-06-28

Review 3.  Does interferon cure cancer?

Authors:  K Sikora
Journal:  Br Med J       Date:  1980-09-27

Review 4.  Interferons and interferon inducers: development of clinical usefulness and therapeutic promise.

Authors:  R B Pollard
Journal:  Drugs       Date:  1982 Jan-Feb       Impact factor: 9.546

Review 5.  Interferon-alpha in malignant and viral diseases. A review.

Authors:  R T Dorr
Journal:  Drugs       Date:  1993-02       Impact factor: 9.546

Review 6.  Pathogenesis of genital HPV infection.

Authors:  A Schneider
Journal:  Genitourin Med       Date:  1993-06

Review 7.  Interferons in the treatment of human papillomavirus diseases.

Authors:  P K Weck; J L Brandsma; J K Whisnant
Journal:  Cancer Metastasis Rev       Date:  1986       Impact factor: 9.264

8.  A comparison of interferon alfa-2a and podophyllin in the treatment of primary condylomata acuminata. The Condylomata International Collaborative Study Group.

Authors: 
Journal:  Genitourin Med       Date:  1991-10

Review 9.  The need for new antiviral agents.

Authors:  D S Freestone
Journal:  Antiviral Res       Date:  1985-12       Impact factor: 5.970

Review 10.  The use of interferon-alpha in virus infections.

Authors:  N B Finter; S Chapman; P Dowd; J M Johnston; V Manna; N Sarantis; N Sheron; G Scott; S Phua; P B Tatum
Journal:  Drugs       Date:  1991-11       Impact factor: 9.546

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