Literature DB >> 526704

Different effects of current strength on inhibitory responses of the mouse vas deferens to methionine- and leucine-enkephalin.

S L Hart, I Kitchen, P R Waddell.   

Abstract

The inhibitory potency of methionine (Met)-enkephalin on the field-stimulated mouse vas deferens was greatly increased by a reduction in current strength whilst that of leucine (Leu)-enkephalin increased only slightly. All currents were submaximal and all muscle twitches were neuronally evoked. These results suggest that inhibitory effects of Met- and Leu-enkephalin in the mouse vas deferens are not commonly mediated and provide a rapid method for ascertaining heterogeneity of enkephalin extracts.

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Year:  1979        PMID： 526704      PMCID： PMC2043713          DOI： 10.1111/j.1476-5381.1979.tb10838.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  9 in total

1.  In vitro pharmacology of the opioid peptides, enkephalins and endorphins.

Authors:  A A Waterfield; R W Smokcum; J Hughes; H W Kosterlitz; G Henderson
Journal:  Eur J Pharmacol       Date:  1977-05-15       Impact factor: 4.432

2.  Evidence against adrenergic motor transmission in the guinea-pig vas deferens.

Authors:  N Ambache; M A Zar
Journal:  J Physiol       Date:  1971-07       Impact factor: 5.182

3.  Log-normal distribution of equiefective doses of norepinephrine and acetylcholine in several tissues.

Authors:  W W Fleming; D P Westfall; I S De la Lande; L B Jellett
Journal:  J Pharmacol Exp Ther       Date:  1972-05       Impact factor: 4.030

4.  Differential behaviour of LPH-(61-91)-peptide in different model systems: comparison of the opioid activities of LPH-(61-91)-peptide and its fragments.

Authors:  A Rónai; L Gráf; I Székely; Z Dunai-Kovács; S Bajusz
Journal:  FEBS Lett       Date:  1977-03-01       Impact factor: 4.124

5.  Electrically stimulated release of opiate-like material from the myenteric plexus of the guinea pig ileum.

Authors:  R Schulz; M Wüster; R Simantov; S Snyder; A Herz
Journal:  Eur J Pharmacol       Date:  1977-02-07       Impact factor: 4.432

6.  Differences in the inhibitory effects of normorphine and opioid peptides on the responses of the vasa deferentia of two strains of mice.

Authors:  A A Waterfield; J A Lord; J Hughes; H W Kosterlitz
Journal:  Eur J Pharmacol       Date:  1978-01-15       Impact factor: 4.432

7.  Effect of morphine on adrenergic transmission in the mouse vas deferens. Assessment of agonist and antogonist potencies of narcotic analgesics.

Authors:  J Hughes; H W Kosterlitz; F M Leslie
Journal:  Br J Pharmacol       Date:  1975-03       Impact factor: 8.739

8.  Adrenergic and 'non-adrenergic' components in the contractile response of the vas deferens to a single indirect stimulus.

Authors:  J C McGrath
Journal:  J Physiol       Date:  1978-10       Impact factor: 5.182

9.  Endogenous opioid peptides: multiple agonists and receptors.

Authors:  J A Lord; A A Waterfield; J Hughes; H W Kosterlitz
Journal:  Nature       Date:  1977-06-09       Impact factor: 49.962
  9 in total
  4 in total

1.  Differential sensitivity of antinociceptive tests to opioid agonists and partial agonists.

Authors:  J S Shaw; J D Rourke; K M Burns
Journal:  Br J Pharmacol       Date:  1988-10       Impact factor: 8.739

2.  Differential effect of stimulation strength in mouse vas deferens on inhibition of neuroeffector transmission by receptor type selective opioids.

Authors:  D Ramme; P Illes
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-01       Impact factor: 3.000

3.  Effects of adrenalectomy and hypophysectomy on enkephalin content of the rat hypothalamus.

Authors:  A Gibson; M Ginsburg; S L Hart; I Kitchen
Journal:  Br J Pharmacol       Date:  1980-12       Impact factor: 8.739

4.  Inhibition of neuroeffector transmission by morphine in the vas deferens of naive and morphine-treated mice.

Authors:  P Illes; R Schulz
Journal:  Br J Pharmacol       Date:  1980       Impact factor: 8.739
  4 in total

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