| Literature DB >> 526544 |
J F Jeannin, M Chessebeuf, M S Martin, A Lagneau, F Martin.
Abstract
In contrast to cholic acid, deoxycholic acid and chenodeoxycholic acid, lithocholic acid (LCA) enhances the growth of rat liver cells in culture. Enhanced proliferation of LCA-treated rat liver cells persists even 12 days after LCA was removed. These findings could suggest a mutagenic effect of LCA, or a metabolite, on rat liver cells.Entities:
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Year: 1979 PMID： 526544
Source DB: PubMed Journal: Biomedicine ISSN： 0300-0893