| Literature DB >> 5263744 |
J B Olmsted, K Carlson, R Klebe, F Ruddle, J Rosenbaum.
Abstract
The addition of vinblastine to high-speed supernatants derived from homogenates of cultured mouse neuroblastoma cells results in the formation of a precipitate which has been characterized as microtubule protein by the following criteria: colchicine-binding activity, molecular weight, amino acid composition, and electrophoretic mobility. The method therefore permits the rapid isolation of microtubule protein from crude supernatants of neuroblastoma cells.Entities:
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Year: 1970 PMID: 5263744 PMCID: PMC286201 DOI: 10.1073/pnas.65.1.129
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205