Literature DB >> 5263743

Sympathetic nerve cell destruction in newborn mammals by 6-hydroxydopamine.

P U Angeletti, R Levi-Montalcini.   

Abstract

A selective and permanent destruction of sympathetic ganglia was achieved by injecting 6-hydroxydopamine in newborn animals. A lifelong chemical sympathectomy may thus be obtained. The process of cell damage and destruction is substantially different from that produced with an antiserum to a specific nerve growth factor.

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Year:  1970        PMID： 5263743      PMCID： PMC286199          DOI： 10.1073/pnas.65.1.114

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  14 in total

1.  Effect of 6-hydroxydopamine and some other compounds on the concentration of norepinephrine in the hearts of mice.

Authors:  C C PORTER; J A TOTARO; C A STONE
Journal:  J Pharmacol Exp Ther       Date:  1963-06       Impact factor: 4.030

2.  EXCESSIVE GROWTH OF THE SYMPATHETIC GANGLIA EVOKED BY A PROTEIN ISOLATED FROM MOUSE SALIVARY GLANDS.

Authors:  R Levi-Montalcini; B Booker
Journal:  Proc Natl Acad Sci U S A       Date:  1960-03       Impact factor: 11.205

3.  PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM.

Authors:  S Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1960-03       Impact factor: 11.205

4.  IN VITRO AND IN VIVO EFFECTS OF A NERVE GROWTH-STIMULATING AGENT ISOLATED FROM SNAKE VENOM.

Authors:  R Levi-Montalcini; S Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1956-09       Impact factor: 11.205

Review 5.  Recent developments on the ultrastructural aspect of adrenergic nerve endings in various experimental conditions.

Authors:  J P Tranzer; H Thoenen; R L Snipes; J G Richards
Journal:  Prog Brain Res       Date:  1969       Impact factor: 2.453

Review 6.  The nerve growth factor (NGF): chemical properties and metabolic effects.

Authors:  P U Angeletti; R Levi-Montalcini; P Calissano
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1968

7.  Immunochemical properties of the nerve growth factor.

Authors:  A Zanini; P Angeletti; R Levi-Montalcini
Journal:  Proc Natl Acad Sci U S A       Date:  1968-11       Impact factor: 11.205

8.  Alterations in the fine structure of nucleoli in sympathetic neurons following NGF-antiserum treatment.

Authors:  R Levi-Montalcini; F Caramia; P U Angeletti
Journal:  Brain Res       Date:  1969-01       Impact factor: 3.252

9.  The relationship between radioactivity and norepinephrine concentrations in the brains and hearts of mice following administration of labeled methyldopa or 6-hydroxydopamine.

Authors:  C C Porter; J A Totaro; A Burcin
Journal:  J Pharmacol Exp Ther       Date:  1965-10       Impact factor: 4.030

10.  Second symposium on catecholamines. Modification of sympathetic function. Immunosympathectomy.

Authors:  R Levi-Montalcini; P U Angeletti
Journal:  Pharmacol Rev       Date:  1966-03       Impact factor: 25.468
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  42 in total

1.  Effects of 6-hydroxydopamine Treatment at birth on the submaxillary gland of the rat.

Authors:  C J Perec; F J Stefano; C M Baratti; O R Tumilasci
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

2.  Effects of neonatal removal of superior cervical ganglion on serotonin and thyrotropin-releasing hormone immunoreactivity in the intermediolateral cell column of the rat spinal cord.

Authors:  P Poulat; L Marlier; F Pellas; N Rajaofetra; A Privat
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

3.  Patterns of destruction of mouse neuroblastoma cells by extracellular hydrogen peroxide formed by 6-hydroxydopamine and ascorbate.

Authors:  Y Zaizen; A Nakagawara; K Ikeda
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

4.  Growth inhibition of sympathetic cells by some adrenergic blocking agents (6-hydroxydopamine-mice and rats-immunosympathectomy-chemical sympathectomy-superior cervical ganglion).

Authors:  P U Angeletti; R Levi-Montalcini
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

5.  Growth characteristics of postnatal rat adrenal medulla in culture. A study correlating phase contrast, microcinematographic, histochemical, and electron microscopical observations.

Authors:  K Unsicker; J H Chamley
Journal:  Cell Tissue Res       Date:  1977-02-09       Impact factor: 5.249

6.  Long-lasting peripheral and central effects of 6-hydroxydopamine in rats.

Authors:  D W Clark; R Laverty; E L Phelan
Journal:  Br J Pharmacol       Date:  1972-02       Impact factor: 8.739

7.  A role for the p75 neurotrophin receptor in axonal degeneration and apoptosis induced by oxidative stress.

Authors:  Bradley R Kraemer; John P Snow; Peter Vollbrecht; Amrita Pathak; William M Valentine; Ariel Y Deutch; Bruce D Carter
Journal:  J Biol Chem       Date:  2014-06-17       Impact factor: 5.157

8.  Action of 6-hydroxydopamine on lamb sympathetic ganglia, vas deferens and adrenal medulla: a combined histochemical, ultrastructural and biochemical comparison with the effects of reserpine.

Authors:  T B Cheah; L B Geffen; B Jarrott; A Ostberg
Journal:  Br J Pharmacol       Date:  1971-08       Impact factor: 8.739

9.  Evaluation of methods for determining 6-hydroxydopamine cytotoxicity.

Authors:  E Tiffany-Castiglioni; J R Perez-Polo
Journal:  In Vitro       Date:  1980-07

10.  The role of post-synaptic neurones in the biochemical maturation of presynaptic cholinergic nerve terminals in a mouse sympathetic ganglion.

Authors:  I B Black; I A Hendry; L L Iversen
Journal:  J Physiol       Date:  1972-02       Impact factor: 5.182
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