| Literature DB >> 526114 |
D Buriot, A M Prieur, Y Lebranchu, J Messerschmitt, C Griscelli.
Abstract
Three children out of a total of 40 who had been treated with chlorambucil for juvenile rheumatoid arthritis developed acute leukaemia. No malignancy was detected in 160 patients in those treated with steroids and/or other anti-inflammatory drugs. Chlorambucil may have induced the malignancies and its use should be avoided in rheumatoid arthritis.Entities:
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Year: 1979 PMID： 526114
Source DB: PubMed Journal: Arch Fr Pediatr ISSN： 0003-9764