Literature DB >> 5261071

Remission induction with cytosine arabinoside and L-asparaginase in acute lymphoblastic leukaemia.

T J McElwain, R M Hardisty.   

Abstract

Nine patients with acute lymphoblastic leukaemia in relapse were treated with a course of cytosine arabinoside followed immediately by a course of L-asparaginase. Eight patients achieved complete remission of their disease. This combination of drugs is sufficiently effective to suggest that further trial is needed. It is possible that the combination has a synergistic effect.

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Year:  1969        PMID： 5261071      PMCID： PMC1630069          DOI： 10.1136/bmj.4.5683.596

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  3 in total

1.  ACTION OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE ON THE NUCLEIC ACID METABOLISM AND VIABILITY OF HELA CELLS.

Authors:  J H KIM; M L EIDINOFF
Journal:  Cancer Res       Date:  1965-06       Impact factor: 12.701

2.  Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults.

Authors:  R R Ellison; J F Holland; M Weil; C Jacquillat; M Boiron; J Bernard; A Sawitsky; F Rosner; B Gussoff; R T Silver; A Karanas; J Cuttner; C L Spurr; D M Hayes; J Blom; L A Leone; F Haurani; R Kyle; J L Hutchison; R J Forcier; J H Moon
Journal:  Blood       Date:  1968-10       Impact factor: 22.113

3.  Drug effect in acute leukemia.

Authors:  B C Lampkin; T Nagao; A M Mauer
Journal:  J Clin Invest       Date:  1969-06       Impact factor: 14.808
  3 in total
  1 in total

1.  L-asparaginase in treatment of acute leukaemia and lymphosarcoma.

Authors:  M E Beard; D Crowther; D A Galton; R J Guyer; G H Fairley; H E Kay; P J Knapton; J S Malpas; R B Scott
Journal:  Br Med J       Date:  1970-01-24
  1 in total

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